Creation of a Multi-User Laboratory for the analysis of three-dimensional images of biological tissues and biomaterials (3D BIOLAB)

• Grant number: 09/54142-5
• Support Opportunities: Multi-user Equipment Program
• Start date: October 01, 2010
• End date: September 30, 2012
• Field of knowledge: Health Sciences - Dentistry - Oral and Maxillofacial Surgery
• Principal Investigator: Adalberto Luiz Rosa
• Grantee: Adalberto Luiz Rosa
• Host Institution: Faculdade de Odontologia de Ribeirão Preto (FORP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• EMU web page: Página do Equipamento Multiusuário não informada
• Type of equipment: Tipo de Equipamento Multiusuário não informado
• Manufacturer: Fabricante não informado
• Model: Modelo não informado

Abstract

This project envisages creation of Multi-user Laboratory for Analysis of Three-Dimensional Images and Biomaterials (LAB 3 BIO). Our proposal has the objective of increasing research capacity at the Microscopy and Image Analysis Laboratory, which current operates within the Department of Surgery and TBMF and Periodontics at Universidade de São Paulo’s School of Odontology (FORP- USP). And to also institutionalize and formalize the multi-user character of structure that has served the demands of several researchers from FORP, other USP units and other institutions. We are proposing officialization of this laboratory as a multiuser unit, according to the attached Management and Sharing Plan, with expansion of this structure in terms of physical area, number of technicians available, equipment and principally quality (and new) services available to users. The LAB 3D BIO will allow scientists to obtain, capture and analyze images of biological tissues, biomaterial and interactions among them. Currently, the equipment available, which represents part of the institutional counterparts, allows for bidimensional studies (2D) of these images and only after material is processed through histological analysis. The equipment requested represents an import complementation because it allows for tridimensional analysis of images - with microtomography images can be obtained from samples before any histological processing. The capacity for analysis, broadened by high resolution, allows for advances in micro and submicrostructure studies of mineralized tissues and its alterations due to pathological process, scarring and response to substances and biomaterials. Bringing together all these resources in one laboratory with available technical support and in the context of our institution’s consolidated research groups will make LAB 3D BIO a national reference in São Paulo State. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FREITAS, GILEADE P.; LOPES, HELENA B.; SOUZA, ALANN T. P.; OLIVEIRA, PAULA G. F. P.; ALMEIDA, ADRIANA L. G.; COELHO, PAULO G.; FERREIRA, FERNANDA U.; COVAS, DIMAS T.; BELOTI, MARCIO M.; ROSA, ADALBERTO L.. Effect of cell therapy with osteoblasts differentiated from bone marrow or adipose tissue stromal cells on bone repair. REGENERATIVE MEDICINE, v. 14, n. 12, p. 1107-1119, DEC 2019. (14/26864-4, 15/21439-6, 09/54142-5)

SOUZA, ALANN THAFFARELL PORTILHO; LOPES, HELENA BACHA; FREITAS, GILEADE PEREIRA; FERRAZ, EMANUELA PRADO; OLIVEIRA, FABIOLA SINGARETTI; ALMEIDA, ADRIANA LUISA GONCALVES; WEFFORT, DENISE; BELOTI, MARCIO MATEUS; ROSA, ADALBERTO LUIZ. Role of embryonic origin on osteogenic potential and bone repair capacity of rat calvarial osteoblasts. JOURNAL OF BONE AND MINERAL METABOLISM, v. 38, n. 4, FEB 2020. (15/21439-6, 09/54142-5)