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The search for the N34S mutation of the SPINK1 gene and the R254W mutation of the CTRC gene in alcoholic patients with and without chronic pancreatitis

Grant number: 11/50042-6
Support Opportunities:Regular Research Grants
Start date: August 01, 2011
End date: July 31, 2013
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Suzane Kioko Ono
Grantee:Suzane Kioko Ono
Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

In recent years many studies have exarnined the genetic predisposition to pancreatic diseases. Pancreatic disease of an alcoholic etiology was determined to be a multi-factorial disease, where environrnental factors interact with the genetic profile of lhe individual. In this research we intend to investigate the frequency of the N34S mutation of the SPINK I gene and the R254 W mutation of the CTRC gene in patients with and without alcoholic chronic pancreatitis, registered at the Departrnent of Gastraenterology. University of São Paulo. (AU)

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