Importance of antirabies revaccination for adequate antirabies protection in bovine newborns

• Grant number: 10/09860-4
• Support Opportunities: Regular Research Grants - Publications - Scientific article
• Start date: August 01, 2010
• End date: January 31, 2011
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
• Principal Investigator: Jane Megid
• Grantee: Jane Megid
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

The transfer of antirabies immunoglobulins in cows that were prime-vaccinated and cows that were revaccinated against rabies correlated to the sera titers in their offspring were evaluated. The results demonstrated that revaccination against rabies during pregnancy induces neutralizing antibody titers at a protective level that are transferred directly to calves through colostrum and reinforce the importance of revaccination for improved colostral antibody transfer and offspring protection against rabies. (AU)