Predictive factors of HPV-Induced cytoarchitecture alteration after operative treatment to cervical intraepithelial neoplasia

• Grant number: 11/19749-6
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2012
• End date: January 31, 2014
• Field of knowledge: Health Sciences - Medicine - Pathological Anatomy and Clinical Pathology
• Principal Investigator: José Humberto Tavares Guerreiro Fregnani
• Grantee: José Humberto Tavares Guerreiro Fregnani
• Host Institution: Hospital do Câncer de Barretos. Fundação Pio XII (FP). Barretos , SP, Brazil
• Associated researchers: Carlos Eduardo Mattos da Cunha Andrade ; Ismael Dale Cotrim Guerreiro da Silva

Abstract

The idealization of this work is based on the search for an improvement in care provided to patients with intraepithelial neoplasia and cervical cancer. And with the use of prognostic factors can correctly anticipate the expected survival and response to treatment of these patients with both as precursor lesions of malignancy. Because cervical cancer has a high rate of incidence and mortality in developing countries like Brazil, and yet has a secondary visibility in the scientific community, having been a recurring theme in some national and international publications, we propose a comprehensive study practical purposes and to better treat these pathologies, defining if there are markers that should be used and how they should be interpreted so that one can predict the entire evolution of a patient who presents with intraepithelial neoplasia of the cervix. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ANDRADE, CARLOS E. M. C.; SCAPULATEMPO-NETO, CRISTOVAM; LONGATTO-FILHO, ADHEMAR; VIEIRA, MARCELO A.; TSUNODA, AUDREY T.; DA SILVA, ISMAEL D. C. G.; FREGNANI, JOSE HUMBERTO T. G.. Prognostic scores after surgical treatment for cervical intraepithelial neoplasia: a proposed model and possible implications for post-operative follow-up. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, v. 93, n. 9, p. 941-948, SEP 2014. (11/19749-6)