Identification of new molecular markers in angiogenic retina and rational design of new therapeutic agents for eye diseases with a vascular component

• Grant number: 08/54806-8
• Support Opportunities: Research Grants - Young Investigators Grants
• Start date: June 01, 2009
• End date: May 31, 2014
• Field of knowledge: Biological Sciences - Biochemistry
• Principal Investigator: Ricardo Jose Giordano
• Grantee: Ricardo Jose Giordano
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 12/18681-1 - Characterization of peptides that interact with receptor tyrosine kinase VEGFR-3, BP.IC; 12/13967-4 - Molecular recognition between Trypanosoma Cruzi and endothelial cells: phage display studies, BP.DD; 10/17998-6 - Identification of vascular targets capable of crossing the blood brain barrier and cerebral vascular diversity study, BP.IC; 09/54844-0 - Identification of retinal angiogenesis molecular markers, BP.PD

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

REIS TEIXEIRA, ANDRE AZEVEDO; SARDINHA DE VASCONCELOS, VERONICA DE CASSIA; COLLI, WALTER; MANSO ALVES, MARIA JULIA; GIORDANO, RICARDO JOSE. Trypanosoma cruzi Binds to Cytokeratin through Conserved Peptide Motifs Found in the Laminin-G-Like Domain of the gp85/Trans-sialidase Proteins. PLoS Neglected Tropical Diseases, v. 9, n. 9, SEP 2015. (08/54806-8, 13/16478-7)

DE OLIVEIRA, HAROLDO C.; MICHALOSKI, JUSSARA S.; DA SILVA, JULHIANY F.; SCORZONI, LILIANA; DE PAULA E SILVA, ANA C. A.; MARCOS, CAROLINE M.; ASSATO, PATRICIA A.; YAMAZAKI, DANIELLE S.; FUSCO-ALMEIDA, ANA M.; GIORDANO, RICARDO J.; et al. Peptides Derived from a Phage Display Library Inhibit Adhesion and Protect the Host against Infection by Paracoccidioides brasiliensis and Paracoccidioides lutzii. FRONTIERS IN PHARMACOLOGY, v. 7, DEC 23 2016. (08/54806-8, 15/14023-8, 15/03700-9, 16/17048-4, 13/10917-9)

Filed patent(s) as a result of this research project