Search for causal polymorphisms in candidate genes selected by genomic analyses e their associations with sexual precocity in Nellore heifers

• Grant number: 11/22163-3
• Support Opportunities: Regular Research Grants
• Start date: March 01, 2012
• End date: February 28, 2014
• Field of knowledge: Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
• Principal Investigator: Humberto Tonhati
• Grantee: Humberto Tonhati
• Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
• Associated researchers: Fabio Ricardo Pablos de Souza ; Fernando Sebastián Baldi Rey ; Lucia Galvão de Albuquerque ; Luciana Correia de Almeida Regitano

Abstract

In beef cattle production, the sexual precocity is a trait with a big importance because of the high economic value associated to it, being three times more important, in genetic-economic values, than growth traits. The genetic parameters are interesting, because it has high heritability values, permitting selection. However, in genomic analyses, is difficult to find the balance between applying a conservative or a relaxed threshold model, so new methodologies were proposed to find genes of interest using previous genomic analyses. So, it is proposed to investigate causal polymophisms in these genes previously indicated as candidates (NCOA2 and TOX)as well as others (JY-1) and establish a possible association with sexual precocity in Nellore heifers (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CARDOSO, D. F.; DE SOUZA, G. F. P.; ASPILCUETA-BORQUIS, R. R.; NETO, F. R. ARAUJO; DE CAMARGO, G. M. F.; HURTADO-LUGO, N. A.; SCALEZ, D. C. B.; DE FREITAS, A. C.; ALBUQUERQUE, L. G.; TONHATI, H.. Short communication: Variable number of tandem repeat polymorphisms in DGAT1 gene of buffaloes (Bubalus bubalis) is associated with milk constituents. JOURNAL OF DAIRY SCIENCE, v. 98, n. 5, p. 3492-3495, MAY 2015. (11/22163-3)