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Search for causal polymorphisms in candidate genes selected by genomic analyses e their associations with sexual precocity in Nellore heifers

Grant number:11/22163-3
Support Opportunities:Regular Research Grants
Start date: March 01, 2012
End date: February 28, 2014
Field of knowledge:Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
Principal Investigator:Humberto Tonhati
Grantee:Humberto Tonhati
Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
City of the host institution:Jaboticabal
Associated researchers: Fabio Ricardo Pablos de Souza ; Fernando Sebastián Baldi Rey ; Lucia Galvão de Albuquerque ; Luciana Correia de Almeida Regitano

Abstract

In beef cattle production, the sexual precocity is a trait with a big importance because of the high economic value associated to it, being three times more important, in genetic-economic values, than growth traits. The genetic parameters are interesting, because it has high heritability values, permitting selection. However, in genomic analyses, is difficult to find the balance between applying a conservative or a relaxed threshold model, so new methodologies were proposed to find genes of interest using previous genomic analyses. So, it is proposed to investigate causal polymophisms in these genes previously indicated as candidates (NCOA2 and TOX)as well as others (JY-1) and establish a possible association with sexual precocity in Nellore heifers (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications
(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)
CARDOSO, D. F.; DE SOUZA, G. F. P.; ASPILCUETA-BORQUIS, R. R.; NETO, F. R. ARAUJO; DE CAMARGO, G. M. F.; HURTADO-LUGO, N. A.; SCALEZ, D. C. B.; DE FREITAS, A. C.; ALBUQUERQUE, L. G.; TONHATI, H.. Short communication: Variable number of tandem repeat polymorphisms in DGAT1 gene of buffaloes (Bubalus bubalis) is associated with milk constituents. JOURNAL OF DAIRY SCIENCE, v. 98, n. 5, p. 3492-3495, . (11/22163-3)