Recombinant antigen targeting to dendritic cells in vivo: a new strategy for the development of vaccines

• Grant number: 07/08648-9
• Support Opportunities: Research Grants - Young Investigators Grants
• Start date: September 01, 2008
• End date: October 31, 2012
• Field of knowledge: Biological Sciences - Immunology - Cellular Immunology
• Principal Investigator: Silvia Beatriz Boscardin
• Grantee: Silvia Beatriz Boscardin
• Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 10/03079-9 - Adaptive Response analysis when a dengue virus antigen is directed to two distinct populations of dendritic cells., BP.MS; 09/12625-0 - Targeting the Plasmodium vivax and Plasmodium yoelii MSP-119 proteins to dendritic cells in vivo: analysis of cellular and humoral immune responses., BP.MS

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

AMORIM, KELLY N. S.; RAMPAZO, ELINE V.; ANTONIALLI, RENAN; YAMAMOTO, MARCIO M.; RODRIGUES, MAURICIO M.; SOARES, IRENE S.; BOSCARDIN, SILVIA B.. The presence of T cell epitopes is important for induction of antibody responses against antigens directed to DEC205(+) dendritic cells. SCIENTIFIC REPORTS, v. 6, DEC 21 2016. (13/11442-4, 07/08648-9)

RAMPAZO, ELINE V.; AMORIM, KELLY N. S.; YAMAMOTO, MARCIO M.; PANATIERI, RAQUEL HOFFMANN; RODRIGUES, MAURICIO M.; BOSCARDIN, SILVIA B.. Antigen Targeting to Dendritic Cells Allows the Identification of a CD4 T-Cell Epitope within an Immunodominant Trypanosoma cruzi Antigen. PLoS One, v. 10, n. 2, FEB 13 2015. (07/08648-9)

AMORIM, KELLY N. S.; CHAGAS, DANIELE C. G.; SULCZEWSKI, FERNANDO B.; BOSCARDIN, SILVIA B.. Dendritic Cells and Their Multiple Roles during Malaria Infection. JOURNAL OF IMMUNOLOGY RESEARCH, v. 2016, p. 11-pg., 2016-01-01. (07/08648-9, 13/11442-4)

AMORIM, KELLY N. S.; CHAGAS, DANIELE C. G.; SULCZEWSKI, FERNANDO B.; BOSCARDIN, SILVIA B.. Dendritic Cells and Their Multiple Roles during Malaria Infection. CLINICAL & DEVELOPMENTAL IMMUNOLOGY, 2016. (13/11442-4, 07/08648-9)

HENRIQUES, HUGO R.; RAMPAZO, ELINE V.; GONCALVES, ANTONIO J. S.; VICENTIN, ELAINE C. M.; AMORIM, JAIME H.; PANATIERI, RAQUEL H.; AMORIM, KELLY N. S.; YAMAMOTO, MARCIO M.; FERREIRA, LUIS C. S.; ALVES, ADA M. B.; et al. Targeting the Non-structural Protein 1 from Dengue Virus to a Dendritic Cell Population Confers Protective Immunity to Lethal Virus Challenge. PLoS Neglected Tropical Diseases, v. 7, n. 7, JUL 2013. (10/03079-9, 07/08648-9)

BOSCARDIN, SILVIA BEATRIZ; TROCCOLI TORRECILHAS, ANA CLAUDIA; MANARIN, ROMINA; REVELLI, SILVIA; GONZALEZ REY, ELENA; TONELLI, RENATA ROSITO; SILBER, ARIEL MARIANO. Chagas' disease: an update on immune mechanisms and therapeutic strategies. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, v. 14, n. 6B, p. 1373-1384, JUN 2010. (07/08648-9)