Development and applications of enzymatic columns in selective inhibitors screening and in the natural products studies

• Grant number: 08/04371-5
• Support Opportunities: Research Grants - Young Investigators Grants
• Start date: October 01, 2008
• End date: March 31, 2013
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Carmen Lúcia Cardoso
• Grantee: Carmen Lúcia Cardoso
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated scholarship(s): 12/10749-6 - Development of capillary columns enzymatic to application of screening of selective inhibitors for the enzyme NTPDase- 2 of Leishmania infantun, BP.DR; 12/01800-8 - Application of capillary bioreactor of acetylcholinesterase in screening of combining collections and natural crude extracts, BP.IC; 08/07526-0 - Immobilized enzyme reactor of acetylcholinesterase on fused silica capillary tube: new format for screening of selective inhibitors screening, BP.MS

Scientific publications

(7)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CALIL, FELIPE ANTUNES; LIMA, JULIANA MARIA; CAVALCANTE DE OLIVEIRA, ARTHUR HENRIQUE; MARIOTINI-MOURA, CHRISTIANE; RANGEL FIETTO, JULIANA LOPES; CARDOSO, CARMEN LUCIA. Immobilization of NTPDase-1 from Trypanosoma cruzi and Development of an Online Label-Free Assay. JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY, 2016. (13/01710-1, 08/04371-5)

DE MORAES, MARCELA C.; VANZOLINI, KENIA L.; CARDOSO, CARMEN L.; CASS, QUEZIA B.. New trends in LC protein ligand screening. Journal of Pharmaceutical and Biomedical Analysis, v. 87, n. SI, p. 155-166, JAN 18 2014. (08/04371-5)

LOPES VILELA, ADRIANA FERREIRA; DA SILVA, JOYCE IZIDORO; CURCINO VIEIRA, LUCAS CAMPOS; BERNASCONI, GILBERTO C. R.; CORREA, ARLENE GONCALVES; CASS, QUEZIA BEZERRA; CARDOSO, CARMEN LUCIA. Immobilized cholinesterases capillary reactors on-flow screening of selective inhibitors. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, v. 968, n. SI, p. 87-93, OCT 1 2014. (08/07526-0, 08/04371-5)

MORAIS, ELIDA P.. . REVISTA VIRTUAL DE QUIMICA, v. 7, n. 6, p. 2334-2346, NOV-DEC 2015. (08/04371-5)

DA SILVA, JOYCE IZIDORO; NICASTRO, PATRICIA CAROLINA; DE OLIVEIRA, PATRICIA C. M.; FOSSALUZZA, POLIANA C.; MORAIS, ELIDA P.; DIAS, KRIS SIMONE T.; DA COSTA, RODRIGO S.; CASTRO, NEWTON G.; CARDOSO, CARMEN LUCIA; VIEGAS, CLAUDIO, JR.. A Comparative Evaluation of Acetylcholinesterase Inhibition by AChE-ICER and in vitro Ellman's Modified Method of Simplified Analogs 3-O-Acetyl-N-Benzyl-Piperidine of Donepezil. REVISTA VIRTUAL DE QUIMICA, v. 7, n. 6, p. 13-pg., 2015-11-01. (08/04371-5)

CALIL, FELIPE ANTUNES; LIMA, JULIANA MARIA; CAVALCANTE DE OLIVEIRA, ARTHUR HENRIQUE; MARIOTINI-MOURA, CHRISTIANE; RANGEL FIETTO, JULIANA LOPES; CARDOSO, CARMEN LUCIA. Immobilization of NTPDase-1 from Trypanosoma cruzi and Development of an Online Label-Free Assay. JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY, v. 2016, p. 9-pg., 2016-01-01. (13/01710-1, 08/04371-5)

DE MORAES, MARCELA C.; VANZOLINI, KENIA L.; CARDOSO, CARMEN L.; CASS, QUEZIA B.. New trends in LC protein ligand screening. Journal of Pharmaceutical and Biomedical Analysis, v. 87, p. 12-pg., 2014-01-18. (08/04371-5)