Quantification and analysis of dynamic structures in PET and SPECT cardiac images

• Grant number: 06/06612-4
• Support Opportunities: Regular Research Grants
• Start date: March 01, 2007
• End date: February 28, 2009
• Field of knowledge: Engineering - Biomedical Engineering
• Principal Investigator: Marina de Fátima de Sá Rebelo
• Grantee: Marina de Fátima de Sá Rebelo
• Host Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil

Abstract

The quantification of dynamic events, like the heart movement, is one of the most challenging applications in the field of image analysis. Cardiac movement analysis is a complex task carried out by a highly qualified specialist and is mainly concerned with pathological motion interpretation, related to coronaries circulation deficiencies, myocardial anomalies or intraventricular electrical conduction deficiencies. Despite its importance, computer-aided dynamic cardiac motion scene interpretation has not been widely studied. The quantitative analysis of global and regional heart movement by means of 3D dynamic PET and SPECT has the potential to increase the diagnoses quality of cardiac diseases in relation to the results currently obtained with these techniques. In the present project we intend to address some steps involved in the 3D dynamic PET and SPECT images quantification process: quantification of the heart movement; image representations able to capture relevant features for image analysis. Specifically we will focus on parameters that can be important for diagnosis and therapy, like the temporal volumetric behavior of 3D dynamic structures and the characterization of movement. We also intend to evaluate friendly and intuitive interfaces for presenting the information to the doctors. The proposed methods will be used in a clinical application: analysis of ventricular dyssynchrony. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

REBELO, MARINA DE SA; HUMMELGAARD AARRE, ANN KIRSTINE; CLEMMESEN, KAREN-LOUISE; SOARES BRANDAO, SIMONE CRISTINA; GIORGI, MARIA CLEMENTINA; MENEGHETTI, JOSE CLAUDIO; GUTIERREZ, MARCO ANTONIO. Determination of Three-Dimensional Left Ventricle Motion to Analyze Ventricular Dyssyncrony in SPECT Images. EURASIP JOURNAL ON ADVANCES IN SIGNAL PROCESSING, 2010. (06/06612-4)

REBELO, MARINA DE SA; HUMMELGAARD AARRE, ANN KIRSTINE; CLEMMESEN, KAREN-LOUISE; SOARES BRANDAO, SIMONE CRISTINA; GIORGI, MARIA CLEMENTINA; MENEGHETTI, JOSE CLAUDIO; GUTIERREZ, MARCO ANTONIO. Determination of Three-Dimensional Left Ventricle Motion to Analyze Ventricular Dyssyncrony in SPECT Images. EURASIP JOURNAL ON ADVANCES IN SIGNAL PROCESSING, v. N/A, p. 9-pg., 2010-01-01. (06/06612-4)