Transcatheter aortic valve implant evaluation using multislice computed tomography

• Grant number: 13/06573-2
• Support Opportunities: Regular Research Grants
• Start date: June 01, 2014
• End date: May 31, 2015
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Diego Felipe Gaia dos Santos
• Grantee: Diego Felipe Gaia dos Santos
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated researchers: Carolina Baeta Neves Duarte Ferreira ; João Roberto Breda ; José Honório de Almeida Palma da Fonseca

Abstract

OBJECTIVES: Transcatheter aortic valve implantation is an established procedure for high-risk patients. There is no consensus about the best method for preoperative and postoperative evaluation of the aortic ring and the implanted prosthesis. The aim is to evaluate pre and post operative aortic ring and aortic prosthesis using multislice computed tomography with three-dimensional reconstruction. METHODS: 30 patients referred for transcatheter aortic valve implantation will undergo computed tomography of multiple detectors before and after surgery. Measurements of aortic valve and prosthesis and will be conducted and correlated with the valve gradient and residual aortic insufficiency.RESULTS: It is expected that the pre and post operative assessment of the aortic valve, aortic prosthesis implanted device will be able to provide important information on the correct selection of the prosthesis size with emphasis on avoiding expansion to hypo or hiper prosthetic device dimension selection with direct consequences on the clinical outcome of patients. Assessments will also be able to possibly contribute to structural improvements and construction of prostheses by understanding their behavior after implantation.CONCLUSION: Multislice Computed tomography evaluation will possibly be able to contribute to better selection and improvement of prosthetic design characteristics of transcatheter prostheses. (AU)