| Grant number: | 14/11763-8 |
| Support Opportunities: | Regular Research Grants |
| Start date: | October 01, 2014 |
| End date: | September 30, 2016 |
| Field of knowledge: | Biological Sciences - Genetics - Animal Genetics |
| Principal Investigator: | Diogo Cavalcanti Cabral-De-Mello |
| Grantee: | Diogo Cavalcanti Cabral-De-Mello |
| Host Institution: | Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil |
| City of the host institution: | Rio Claro |
Abstract
The analysis of experimental models for knowledge of sex chromosomes evolution progressively advance and currently the molecular cytogenetic and genomic data has been explored for this proposes. In crickets and in some grasshopper species wide diversity of sex chromosomes systems have been observed, occurring X0/XX, neo-XY/XX, neo-X1X2Y/X1X1X2X2 and X1X20/X1X1X2X2, originated by distinct chromosomal rearrangements between autosomes and sex chromosomes. Although these systems have been studied only through classical cytogenetics and no information are available concerning molecular composition of these chromosomes. Due the occurrence of distinct mechanisms, in distinct stages of differentiation, the crickets and grasshoppers could be good experimental model to the understanding of origin/diversification patterns of sex chromosomes. Thus, the objective of this work is to analyze the structure and evolutionary patterns of distinct sex chromosome systems based in the analysis of distinct repetitive DNAs, such multigene families, satellite DNAs, microsatellites, transposable elements, microdissection and chromosome painting, associated to genomic data obtained from completely sequenced genomes and analysis by immunolocalization. The model species present distinct sex chromosome systems, including X0, X1X20, neo-XY and neo-X1X2Y, being Eneoptera surinamensis (neo-X1X2Y) and Ronderosia bergi (neo-XY) the main biological models for the work. The possibility of the integration of genomic (such as, for example, whole sequenced genomes and isolation of sequences specifically from sex chromosomes) and chromosomal data (obtained from classical cytogenetics and physical chromosome mapping) became real with the advent of new technologies. The association of these data in ortopterans will allow a deeper knowledge related to structure, molecular composition and evolution of sex chromosomes in the group. These data will useful to the proposition of hypotheses that raise the origin/evolution of derived sex chromosomes and the test of them. (AU)
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