Microelectronic biossensors associated with electrochemical techniques

• Grant number: 14/09562-4
• Support Opportunities: Regular Research Grants
• Start date: December 01, 2014
• End date: November 30, 2016
• Field of knowledge: Engineering - Electrical Engineering - Electrical, Magnetic and Electronic Measurements, Instrumentation
• Principal Investigator: Marcelo Mulato
• Grantee: Marcelo Mulato
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• City of the host institution: Ribeirão Preto
• Associated researchers: Adalgisa Rodrigues de Andrade
• Associated research grant(s): 15/50082-9 - Towards novel biosensor devices for improved Cancer diagnosis, AP.R SPRINT

Abstract

The development of new biosensors is important to the medical field. The miniaturization of these devices will perform less invasive procedures, reducing the amount of sample to be analyzed, possibly faster responses and easy microelectronic processing. Additionally, studies of new materials could develop devices with higher sensitivity and selectivity. This project proposes the study and comparison of microelectronic biosensors with selective layer for pH and / or specific biostructures using oxide films and DNA films. It may be mentioned glucose, urea and specific DNA sequences. There will be the proposed selective materials optimization using electrochemical techniques such as cyclic voltammetry and electrochemical impedance spectroscopy. The analysis of developed prototype biosensors will be complemented with experiments using field effect transistors with extended gate and quartz crystal microbalance in order to compare electric results with gravimetric results. Thus, the construction of biosensors for their application in large scale and low cost are expected. (AU)

Scientific publications

(13)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CONDELES, J. F.; MULATO, M.. Polycrystalline lead iodide films produced by solution evaporation and tested in the mammography X-ray energy range. JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS, v. 89, p. 39-44, FEB 2016. (14/09562-4)

CONDELES, J. F.; MULATO, M.. Crystalline texture and mammography energy range detection studies of pyrolysed lead iodide films: Effects of solution concentration. Materials Chemistry and Physics, v. 166, p. 190-195, SEP 15 2015. (14/09562-4)

PEDROZA DIAS MELLO, HUGO JOSE NOGUEIRA; MULATO, MARCELO. Influence of galvanostatic electrodeposition parameters on the structure-property relationships of polyaniline thin films and their use as potentiometric and optical pH sensors. Thin Solid Films, v. 656, p. 14-21, JUN 30 2018. (14/09562-4, 14/24559-0)

PEDROZA DIAS MELLO, HUGO JOSE NOGUEIRA; MULATO, MARCELO. Effect of aniline monomer concentration on PANI electropolymerization process and its influence for applications in chemical sensors. Synthetic Metals, v. 239, p. 66-70, MAY 2018. (14/09562-4, 14/24559-0)

PEDROZA DIAS MELLO, HUGO JOSE NOGUEIRA; MULATO, MARCELO. Enzymatically functionalized polyaniline thin films produced with one-step electrochemical immobilization and its application in glucose and urea potentiometric biosensors. BIOMEDICAL MICRODEVICES, v. 22, n. 1, FEB 27 2020. (14/09562-4, 14/24559-0, 17/24201-6)

SANCHES NASCIMENTO, RAPHAEL APARECIDO; MULATO, MARCELO. Mechanisms of Ion Detection for FET-Sensors Using FTO: Role of Cleaning Process, pH Sequence and Electrical Resistivity. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 20, n. 5, p. 11-pg., 2017-09-01. (14/09562-4)

PEDROZA DIAS MELLO, HUGO JOSE NOGUEIRA; MANO, FERNANDO MACEDO; MULATO, MARCELO; IEEE. A multimodal array of enzymatic biosensors: effect of solution's pH and REFET film. 2017 32ND SYMPOSIUM ON MICROELECTRONICS TECHNOLOGY AND DEVICES (SBMICRO): CHIP ON THE SANDS, v. N/A, p. 4-pg., 2017-01-01. (14/09562-4, 14/24559-0)

SANCHES NASCIMENTO, RAPHAEL APARECIDO; MULATO, MARCELO. Mechanisms of Ion Detection for FET-Sensors Using FTO: Role of Cleaning Process, pH Sequence and Electrical Resistivity. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 20, n. 5, p. 1369-1379, SEP-OCT 2017. (14/09562-4)

PEDROZA DIAS MELLO, HUGO JOSE NOGUEIRA; MULATO, MARCELO. Well-established materials in microelectronic devices systems for differential-mode extended-gate field effect transistor chemical sensors. MICROELECTRONIC ENGINEERING, v. 160, p. 73-80, JUL 1 2016. (14/09562-4, 14/24559-0)

PEDROZA DIAS MELLO, HUGO JOSE NOGUEIRA; HEIMFARTH, TOBIAS; MULATO, MARCELO. Influence of the physical-chemical properties of polyaniline thin films on the final sensitivity of varied field effect sensors. Materials Chemistry and Physics, v. 160, p. 257-263, JUN 15 2015. (14/09562-4, 09/09163-4)

PEDROZA DIAS MELLO, HUGO JOSE NOGUEIRA; MULATO, MARCELO. Optochemical sensors using electrodeposited polyaniline films: Electrical bias enhancement of reflectance response. SENSORS AND ACTUATORS B-CHEMICAL, v. 213, p. 195-201, JUL 5 2015. (14/09562-4, 09/09163-4)

BATISTUTI, MARINA R.; BUENO, PAULO R.; MULATO, MARCELO. The importance of the assembling of DNA strands on the performance of electrochemical genosensors. Microchemical Journal, v. 159, DEC 2020. (17/24839-0, 15/14403-5, 14/09562-4)

PEDROZA DIAS MELLO, HUGO JOSE NOGUEIRA; MULATO, MARCELO. PANI/PPY blend thin films electrodeposited for use in EGFET sensors. Journal of Applied Polymer Science, v. 135, n. 33, SEP 5 2018. (14/24559-0, 14/09562-4)