Development of biocatalytic systems for oxidation and reduction reactions

• Grant number: 14/22457-5
• Support Opportunities: Regular Research Grants
• Start date: March 01, 2015
• End date: February 28, 2017
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Leandro Helgueira de Andrade
• Grantee: Leandro Helgueira de Andrade
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Oxidation and reduction reactions of organic compounds are widely applied in organic chemistry. Usually, they can be used for different synthetic purposes as well as in the degradation of pollutants. In this project we decided to develop biocatalytic systems for application in different molecular targets, such as boron compounds, nitrogen and lignin-like compounds. Furthermore, enzymatic purification and biochemical characterization of oxidoreductase from Arthrobacter will be studied. (AU)

Scientific publications

(5)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CORREIA, VALQUIRIO G.; ABREU, JULIANA C.; BARATA, CAIO A. E.; ANDRADE, LEANDRO H.. Iron-Catalyzed Synthesis of Oxindoles: Application to the Preparation of Pyrroloindolines. ORGANIC LETTERS, v. 19, n. 5, p. 1060-1063, MAR 3 2017. (16/05633-0, 13/04540-0, 14/22457-5)

SANTOS, WAGNER C. C.; DIAS, KEVIN A.; SANTOS, LEIDAIANY P.; KISUKURI, CAMILA M.; RODRIGUES, THENNER S.; GEONMONOND, RAFAEL S.; CAMARGO, PEDRO H. C.; ANDRADE, LEANDRO H.. Evaluating Gold and Selenium Chemistry for Selective Transformations of Lignin Model Compounds. ADVANCED SYNTHESIS & CATALYSIS, v. 360, n. 7, p. 1376-1383, APR 3 2018. (15/21366-9, 14/22457-5)

KISUKURI, CAMILA M.; REIS, JOAO L. M. S.; RODRIGUES, THENNER S.; CAMARGO, PEDRO H. C.; ANDRADE, LEANDRO H.. Evaluation of AgPd Nanoshells in Dual Catalysis: One-Pot Silane Oxidation and Reduction of Organic Compounds. CHEMCATCHEM, v. 8, n. 23, p. 3657-3662, DEC 7 2016. (14/22457-5)

DA SILVA, ANDERSON G. M.; KISUKURI, CAMILA M.; RODRIGUES, THENNER S.; CANDIDO, EDUARDO G.; DE FREITAS, ISABEL C.; DA SILVA, ALISSON H. M.; ASSAF, JOSE M.; OLIVEIRA, DANIELA C.; ANDRADE, LEANDRO H.; CAMARGO, PEDRO H. C.. MnO2 nanowires decorated with Au ultrasmall nanoparticles for the green oxidation of silanes and hydrogen production under ultralow loadings. APPLIED CATALYSIS B-ENVIRONMENTAL, v. 184, p. 35-43, MAY 5 2016. (14/22457-5)

ANDRADE, LEANDRO H.; SOUSA, BRUNO A.; JAMISON, TIMOTHY F.. Confining a Biocatalyst for Highly Efficient and Selective Synthesis of Carboxamide Derivatives under Continuous-Flow Conditions. JOURNAL OF FLOW CHEMISTRY, v. 6, n. 2, p. 67-72, JUN 2016. (14/22457-5, 13/04540-0)