Development of ceramic composites of Si3N4-SiO2-CaO system for bone compatibility

• Grant number: 15/02265-7
• Support Opportunities: Regular Research Grants
• Start date: July 01, 2015
• End date: June 30, 2017
• Field of knowledge: Engineering - Materials and Metallurgical Engineering - Nonmetallic Materials
• Principal Investigator: Cecília Chaves Guedes e Silva
• Grantee: Cecília Chaves Guedes e Silva
• Host Institution: Instituto de Pesquisas Energéticas e Nucleares (IPEN). Secretaria de Desenvolvimento Econômico (São Paulo - Estado). São Paulo , SP, Brazil
• Associated researchers: Andrea Cecilia Dorión Rodas ; Olga Zazuco Higa

Abstract

Considering the ceramic materials investigated for biomedical applications, those based on silicon nitride have presented great potentiality owing to the high mechanical strength, relatively high fracture toughness and low density. However, the biocompatibility of these ceramics depends on the features of intergranular phases usually present and required to produce the final components. Hence, the present project will contribute to the development of silicon nitride containing a second phase depending upon the SiO2-CaO system. Silica and calcia will be added to the initial powder of silicon nitride to promote the biocomposite consolidation with great mechanical properties after sintering. Moreover, it is expected to obtain a bioactive material due to the Si-OH groups formed during the contact with body fluids, promoting deposition of apatite on the surface. The influence of different oxides amounts on the biocomposites will be evaluated in terms of densification, microstructure, mechanical properties and in vitro bioactivity. (AU)

Scientific publications

(8)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GUEDES-SILVA, CECILIA CHAVES; DORION RODAS, ANDREA CECILIA; SILVA, ANTONIO CARLOS; RIBEIRO, CHRISTIANE; DE SOUZA CARVALHO, FLAVIO MACHADO; HIGA, OLGA ZAZUCO; FERREIRA, THIAGO DOS SANTOS. Microstructure, Mechanical Properties and in vitro Biological Behavior of Silicon Nitride Ceramics. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 21, n. 6, 2018. (15/02265-7)

SONA FILHO, CELSO RICARDO; DE SOUZA CARVALHO, FLAVIO MACHADO; GUEDES-SILVA, CECILIA CHAVES. echanical properties and in vitro bioactivity of silicon nitride ceramics with SiO2, CaO, and MgO addition. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, v. 110, n. 3, SEP 2021. (15/02265-7)

T. S. FERREIRA; F. M. S. CARVALHO; C. C. GUEDES-SILVA. Oxidation behavior of Si3N4-TiN composites at 1400 oC. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 26, 2023-11-13. (15/02265-7)

JURASKI, AMANDA DE CASTRO; DORION RODAS, ANDREA CECILIA; ELSAYED, HAMADA; BERNARDO, ENRICO; SOARES, VIVIANE OLIVEIRA; DAGUANO, JULIANA. The In Vitro Bioactivity, Degradation, and Cytotoxicity of Polymer-Derived Wollastonite-Diopside Glass-Ceramics. MATERIALS, v. 10, n. 4, APR 2017. (15/02265-7)

DO NASCIMENTO, SERGIO FERREIRA; DORION RODAS, ANDREA CECILIA; DE SOUZA CARVALHO, FLAVIO MACHADO; HIGA, OLGA ZAZUCO; GUEDES E SILVA, CECILIA CHAVES. Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements. MATERIA-RIO DE JANEIRO, v. 25, n. 4, 2020. (15/02265-7)

DAGUANO, JULIANA K. M. B.; MILESI, MARIANA T. B.; RODAS, ANDREA C. D.; WEBER, ALINE F.; SARKIS, JORGE E. S.; HORTELLANI, MARCOS A.; ZANOTTO, EDGAR D.. In vitro biocompatibility of new bioactive lithia-silica glass-ceramics. Materials Science & Engineering C-Materials for Biological Applications, v. 94, p. 117-125, JAN 1 2019. (15/02265-7)

T. S. FERREIRA; F. M. S. CARVALHO; C. C. GUEDES-SILVA. Densification and microstructure of Si3N4-TiN ceramic composites. Cerâmica, v. 65, p. 87-91, 2019-01-00. (15/02265-7)

GUEDES-SILVA, CECILIA C.; RODAS, ANDREA C. D.; CARVALHO, FLAVIO M. S.; HIGA, OLGA Z.; FERREIRA, THIAGO S.. Silicon nitride with titania, calcia and silica additives for orthopaedic applications. PROCESSING AND APPLICATION OF CERAMICS, v. 14, n. 1, p. 63-70, 2020. (15/02265-7)