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Melatonin is an Ergogenic Aid for Exhaustive Aerobic Exercise only during the Wakefulness Period

Grant number: 15/19878-1
Support Opportunities:Regular Research Grants - Publications - Scientific article
Duration: November 01, 2015 - February 29, 2016
Field of knowledge:Health Sciences - Physical Education
Principal Investigator:Wladimir Rafael Beck
Grantee:Wladimir Rafael Beck
Host Institution: Faculdade de Ciências Aplicadas (FCA). Universidade Estadual de Campinas (UNICAMP). Limeira , SP, Brazil


This study tested the ergogenic effects of acute administration of melatonin on exhaustive exercise (tlim) at the anaerobic threshold intensity (iAnT) during periods of lower (L) and higher (H) spontaneous physical activity in swimming rats. Additionally, we evaluated the time of day effect on aerobic exercise tolerance. The periods of L and H were determined gravimetrically. All animals were subjected to an incremental test to determine the iAnT. Melatonin was administered (10, intraperitoneal) and after 30 minutes, the rats were subjected to tlim during the L (LM) or H (HM) period. Control groups were called LC and HC. The criterion of significance was 5%. Melatonin enhanced tlim by 169% during H (HC = 72 min; HM = 194 min; P < 0.01; ES = 1.23) and by 90% during L (LC = 31 min vs LM = 59 min; P = 0.39; ES = 1.18), demonstrating a significant effect on tlim (F = 10,35; P < 0.01) and a strong effect size (ES). Additionally, tlim was higher during H (F = 14.24; P < 0.01). Melatonin is a reasonable ergogenic aid, particularly during the wakefulness period, and the exercise tolerance is dependent on the time of day for swimming rats. (AU)

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