Identification of genotypes Blastocystis spp. in stool sample and its relation with chronic urticaria

• Grant number: 15/18213-6
• Support Opportunities: Regular Research Grants
• Duration: June 01, 2016 - November 30, 2018
• Field of knowledge: Biological Sciences - Parasitology - Protozoology of Parasites
• Principal Investigator: Ronaldo Cesar Borges Cryschek
• Grantee: Ronaldo Cesar Borges Cryschek
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: Celina Wakisaka Maruta ; Elenice Messias Do Nascimento Gonçalves ; Fabiana Martins de Paula ; Fernanda de Mello Malta ; Gessica Baptista de Melo ; Maria Cristina Carvalho Do Espírito Santo ; Paulo Ricardo Criado ; Vera Lucia Pagliusi Castilho

Abstract

Blastocystis spp. is a protozoan commonly found in stool samples, described as enteroparasite of humans and animals. This organism has a worldwide distribution with an increasing prevalence over the years, but remains surrounded by controversies about aspects such as pathogenicity and zoonotic character. Blastocystis spp. has been related as a possible etiologic agent of gastrointestinal and extraintestinal manifestations such as irritable bowel syndrome, as well as participation in the pathogenesis of chronic urticaria. There are few studies conducted in Brazil with the objective of molecular characterization of subtypes. In view of this, the study aims to identify the subtypes of Blastocytis spp. in stool samples from individuals of the Hospital das Clínicas of Sao Paulo (HC/FMUSP) and possibly understand the relationship of subtypes with chronic urticaria. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GESSICA BAPTISTA DE MELO; WILLIAM ROLDAN; FERNANDA DE MELLO MALTA; SUSANA ANGELICA ZEVALLOS LESCANO; VERA LÚCIA CASTILHO; ELENICE MESSIAS DO NASCIMENTO GONÇALVES; FABIANA MARTINS DE PAULA; RONALDO CESAR BORGES GRYSCHEK. Culture isolation and molecular identification of Blastocystis sp. in Brazilian human isolates: preliminary results. Revista do Instituto de Medicina Tropical de São Paulo, v. 62, 2020-07-13. (15/18213-6)

SILVA, MARIA DO ROSARIO A.; MELO, GESSICA B.; MALTA, FERNANDA M.; ABDALA, EDSON; COSTA, SILVIA F.; PIERROTTI, LIGIA C.; GONCALVES, ELENICE M. N.; CASTILHO, VERA L. P.; CHIEFFI, PEDRO P.; GRYSCHEK, RONALDO C. B.; et al. Subtypes of Blastocystis sp. isolated in fecal samples from transplant candidates in Sao Paulo, Brazil. PARASITE EPIDEMIOLOGY AND CONTROL, v. 8, FEB 2020. (15/18213-6, 10/51110-2)

DE MELO, GESSICA BAPTISTA; BOSQUI, LARISSA RODRIGUES; DA COSTA, IDESSANIA NAZARETH; DE PAULA, FABIANA MARTINS; BORGES GRYSCHEK, RONALDO CESAR. Current status of research regarding Blastocystis sp., an enigmatic protist, in Brazil. Clinics, v. 76, 2021. (15/18213-6)