Histone genes cluster in Rhynchosciara americana and its transcription profile in salivary glands during development

• Grant number: 16/10428-6
• Support Opportunities: Regular Research Grants - Publications - Scientific article
• Start date: August 01, 2016
• End date: January 31, 2017
• Field of knowledge: Biological Sciences - Biochemistry - Molecular Biology
• Principal Investigator: Fábio Siviero
• Grantee: Fábio Siviero
• Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

In this work we report the characterization of Rhynchosciara americana histone genes cluster nucleotide sequence. It spans 5131 bp and contains the four core histones and the linker histone H1. The putative control elements were detected. We also determined the copy number of the tandem repeating unit through real time PCR and the unequivocal chromosome location of its unique locus in chromosome A band 13. These data were compared with the histone clusters from Drosophila genus, which are the closest known homologues. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FÁBIO SIVIERO; PAULA REZENDE-TEIXEIRA; ALEXANDRE DE ANDRADE; ROBERTO VICENTE SANTELLI; GLAUCIA MARIA MACHADO-SANTELLI. The histone genes cluster in Rhynchosciara americana and its transcription profile in salivary glands during larval development. GENETICS AND MOLECULAR BIOLOGY, v. 39, n. 4, p. 580-588, 2016-10-10. (16/10428-6)