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Quantitative MRI of cerebral perfusion at high spatial resolution.

Abstract

Contrast enhanced MRI affords high resolution maps of different hemodynamic parameters; however, the quantification of perfusion using such techniques has been difficult. On the other hand, Arterial Spin Labeling (ASL) methods can accurately map cerebral perfusion but at low spatial resolution. The objective of the present study is to develop a new method that combines contrast enhanced with ASL images to generate quantitative maps of the cerebral perfusion at high spatial resolution. The results of this study may have a significant impact in the clinical practice, improving neuroradiological diagnostics and surgical planning. (AU)

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