Development of Cold Atmospheric Pressure Plasma Jets for Material Treatment, Thin Films Deposition and Biomedical Applications

• Grant number: 15/21989-6
• Support Opportunities: Regular Research Grants
• Start date: September 01, 2016
• End date: August 31, 2018
• Field of knowledge: Physical Sciences and Mathematics - Physics - Physics of Fluids, Plasma Physics and Electrical Discharge
• Principal Investigator: Konstantin Georgiev Kostov
• Grantee: Konstantin Georgiev Kostov
• Host Institution: Faculdade de Engenharia (FEG). Universidade Estadual Paulista (UNESP). Campus de Guaratinguetá. Guaratinguetá , SP, Brazil
• Associated researchers: Cristiane Yumi Koga Ito ; Leide Lili Gonçalves da Silva Kostov ; Milton Eiji Kayama

Abstract

In the last decade the cold atmospheric pressure plasma jets or plumes attracted much attention and have been extensively studied because of innumerous technological applications. Their most important feature is the possibility of generating non-thermal plasma at high pressure, such as atmospheric pressure. The great advantage of the plasma jets is that they can be applied to large and or unregular surfaces and inside narrow spaces (as tooth canal, catheters etc.). Furthermore, the plasma jets can be used for localized treatments on living tissues (treatment of skin cancer, wounds, etc.). However due to the size and rigiditiy of the present plasma jet systems, there is a limitation for their medical applications especially in the case of applications involving treatment of internal organs of the human body. This research project proposes a novel method for production of cold plasma jet at the end of a flexible plastic tube with a length up to a few meters. Thus, the plasma jet is generated far from the high-voltage region and can easily be handled for treatment and sterilization of materials. Thus the aim of this proposal is firstly the development, characterization and optimization of a plasma jet system, which is produced at the end of long plastic tube. As an applications it is intended to treat different materials (polymers, alloys, fabrics, fibers etc.) with the remote plasma jet in order to improve their surface properties such as wettability, adhesion, surface roughness, etc. Besides, the plasma jet at the end of long tube will be tested as a sterilizing agent of biologically contaminated material. We intend to carry out experiments in vitro (bacterial cultures and biofilms) and in vivo (in laboratory animals). In the second place a system for deposition of thin polymers films using cold atmospheric pressure plasma jet will de developed.The produced films will be used as protective coatings and for improvment of surface properties, such as wettability, bio-compartibility, roughness etc. (AU)

Scientific publications

(8)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MUI, TAIANA SHE MIR; MOTA, ROGERIO PINTO; QUADE, ANTJE; DE OLIVEIRA HEIN, LUIS ROGERIO; KOSTOV, KONSTANTIN GEORGIEV. Uniform surface modification of polyethylene terephthalate (PET) by atmospheric pressure plasma jet with a horn-like nozzle. SURFACE & COATINGS TECHNOLOGY, v. 352, p. 338-347, OCT 25 2018. (15/21989-6)

PRYSIAZHNYI, VADYM; SATURNINO, VINICIUS F. B.; KOSTOV, KONSTANTIN G.. Transferred plasma jet as a tool to improve the wettability of inner surfaces of polymer tubes. INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION, v. 22, n. 3, p. 215-221, 2017. (13/06732-3, 15/21989-6)

PRYSIAZHNYI, VADYM; RICCI CASTRO, ALONSO H.; KOSTOV, KONSTANTIN G.. Properties of Atmospheric Pressure Ar Plasma Jet Depending on Treated Dielectric Material. Brazilian Journal of Physics, v. 47, n. 1, p. 65-71, FEB 2017. (13/06732-3, 15/21989-6)

NISHIME, THALITA M. C.; WAGNER, ROBERT; KOSTOV, KONSTANTIN G.. Study of Modified Area of Polymer Samples Exposed to a He Atmospheric Pressure Plasma Jet Using Different Treatment Conditions. POLYMERS, v. 12, n. 5, MAY 2020. (15/21989-6)

DO NASCIMENTO, FELLYPE; MACHIDA, MUNEMASA; KOSTOV, KONSTANTIN; MOSHKALEV, STANISLAV; HONDA, ROBERTO Y.; MOTA, ROGERIO P.; NISHIME, THALITA M. C.; CASTRO, ALONSO H. R.. Enhanced energy transfer efficiency in a four-electrodes configuration DBD plasma jet. EUROPEAN PHYSICAL JOURNAL D, v. 71, n. 11, NOV 7 2017. (15/21989-6)

BORGES, ALINE CHIODI; CASTALDELLI NISHIME, THALITA MAYUMI; KOSTOV, KONSTANTIN GEORGIEV; GOUVEA LIMA, GABRIELA DE MORAIS; LACERDA GONTIJO, ALINE VIDAL; MARTINS MARCHESOTTI DE CARVALHO, JULIANA NOBREGA; HONDA, ROBERTO YZUMI; KOGA-ITO, CRISTIANE YUMI. Cold atmospheric pressure plasma jet modulates Candida albicans virulence traits. CLINICAL PLASMA MEDICINE, v. 7-8, p. 9-15, DEC 2017. (15/03470-3, 16/07196-6, 14/02354-7, 15/21989-6)

BORGES, ALINE CHIODI; CASTALDELLI NISHIME, THALITA MAYUMI; ROVETTA, SABRINA DE MOURA; GOUVEA LIMA, GABRIELA DE MORAIS; KOSTOV, KONSTANTIN GEORGIEV; THIM, GILMAR PATROCINIO; CANUTO DE MENEZES, BEATRIZ ROSSI; BARROS MACHADO, JOAO PAULO; KOGA-ITO, CRISTIANE YUMI. Cold Atmospheric Pressure Plasma Jet Reduces Trichophyton rubrum Adherence and Infection Capacity. Mycopathologia, v. 184, n. 5, p. 585-595, OCT 2019. (14/02354-7, 15/21989-6, 16/07196-6)

BORGES, ALINE CHIODI; GOUVEA LIMA, GABRIELA DE MORAIS; CASTALDELLI NISHIME, THALITA MAYUMI; LACERDA GONTIJO, ALINE VIDAL; KOSTOV, KONSTANTIN GEORGIEV; KOGA-ITO, CRISTIANE YUMI. Amplitude-modulated cold atmospheric pressure plasma jet for treatment of oral candidiasis: In vivo study. PLoS One, v. 13, n. 6, JUN 27 2018. (16/07196-6, 14/02354-7, 15/21989-6)