Hemoparasitoses in dogs: clinical, laboratory and molecular profile for Rickettsia rickettsii, Ehrlichia canis, Rangelia vitallii, Babesia canis vogeli and Bartonella sp. in neglected areas and transmission risk in São Paulo

• Grant number: 16/00167-0
• Support Opportunities: Regular Research Grants
• Start date: November 01, 2016
• End date: April 30, 2019
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
• Principal Investigator: Jonas Moraes Filho
• Grantee: Jonas Moraes Filho
• Host Institution: Universidade de Santo Amaro (UNISA). São Paulo , SP, Brazil
• Associated researchers: Arlei Marcili ; Marcelo Bahia Labruna ; Thiago Fernandes Martins

Abstract

Canine monocytic ehrlichiosis (EMC) in Brazil has shown growing series in veterinary hospitals and clinics, and is considered by many as one of the most important communicable diseases in the clinic for small animals. Another important hemoparasite in dogs and rangeliose or nambyuvú (ear bleeding), also known as yellow fever and fever blood dogs caused by infection with Rangelia Vitalii. Rocky Mountain spotted fever is now recognized as a zoonotic disease transmitted by ticks in Brazil, caused by the bacterium Rickettsia rickettsii. Bacteria Bartonella spp. are belonging to the class of Proteobacteria, with great potential zoonotic and high incidence in different regions of the world, infecting mammalian hosts and reservoirs in which the transmission is associated with different vectors such as ticks, fleas and lice. Canine babesiosis is a tick-borne disease, caused by Babesia hematozoa the genre, in which the B. canis vogeli is the most prevalent in Brazil, regardless of age or breed of animal. Recently, clinical cases other piroplasma, Rangelia Vitalii, have reemerged in the Southeast, especially in São Paulo. For a better understanding of an accurate diagnosis on the main hemoparasitoses that affect dogs treated at the medical clinic, which often are diagnosed in the wrong way, this project has the general objective to evaluate infection by Ehrlichia canis, R. Vitalii, R . rickettsii, B. vogeli and Bartonella spp kennels. in dogs treated at the Veterinary Hospital of the University of Santo Amaro with a clinical suspicion of hemoparasitoses through molecular diagnosis, correlating with the data found in the blood count, biochemical, clinical and physico presented by these patients during the development of the disease.The results of this research project will provide for a better understanding of an accurate diagnosis on the main hemoparasitoses that affect dogs treated at the medical clinic. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Z.Ê.S. SOUZA; B.V. MORAES; F.S. KRAWCZAK; L. ZULZKE; T.V. CARVALHO; A.O. SOUSA; R.G. AGOPIAN; A. MARCILI; M.B. LABRUNA; J. MORAES-FILHO. Detecção de anticorpos anti-Rickettsia rickettsii em cães residentes em área negligenciada no município de São Paulo, SP, Brasil. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 72, n. 6, p. 2141-2147, 2020-11-27. (16/00167-0)

VIEIRA DE CARVALHO, TANIA REGINA; LABRUNA, MARCELO BAHIA; MARCILI, ARLEI; DE SOUSA, AMANDA OLIVEIRA; SOUZA, ZAHI ENI SANTOS; MACHEIA, PIETRO DEMBERI; VALERY, BEATRIZ DE MORAES; REGGIANI, DANIELA GABRIEL; LIMA, DANIEL MAGALHAES; MARTINS, THIAGO FERNANDES; et al. urvey of Brazilian spotted fever in dogs and ticks in Itu, Sao Paulo state, Brazi. INTERNATIONAL JOURNAL OF ACAROLOGY, v. 48, n. 1, DEC 2021. (16/00167-0)