Brazilian national center for molecular diagnosis in inherited cardiac arrhythmias

• Grant number: 16/15223-3
• Support Opportunities: Research Grants - Research in Public Policies for the National Health Care System (PP-SUS)
• Start date: December 01, 2016
• End date: November 30, 2018
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Agreement: CNPq - PPSUS
• Principal Investigator: Alexandre da Costa Pereira
• Grantee: Alexandre da Costa Pereira
• Host Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil

Abstract

Sudden cardiac death is an important cause of mortality, particularly in young. The goal of this project is to implement a rational family screening program in the public health system to prevent sudden cardiac death. The proposed model enables delivery of genetic predictive tool in decentralized fashion with standardization of points of care to support arrhythmia centers in Brazil. The proposal encompasses also training and continuous education to give a broad access to the genetic testing in general. We will focus initially at patients from the Heart Institute of the Faculty of Medicine, University of São Paulo (InCor-HCFMUSP) and rapidly expand to the various partners centers of arrhythmia similarly to what we have accomplished with the Hipercol Brasil. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SACILOTTO, LUCIANA; SCANAVACCA, MAURICIO I.; OLIVETTI, NATALIA; LEMES, CAROLINA; PESSENTE, GABRIELLE D.; WULKAN, FANNY; HACHUL, DENISE T.; KRIEGER, JOSE E.; PEREIRA, ALEXANDRE C.; DARRIEUX, FRANCISCO C. C.; et al. Low rate of life-threatening events and limitations in predicting invasive and noninvasive markers of symptoms in a cohort of type 1 Brugada syndrome patients: Data and insights from the GenBra registry. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, v. 31, n. 11, p. 2920-2928, NOV 2020. (16/15223-3)

OLIVETTI, NATALIA SANGIORGI; SACILOTTO, LUCIANA; WULKAN, FANNY; PESSENTE, GABRIELLE D'AREZZO; DE CARVALHO, MARIANA LOMBARDI PERES; MOLETA, DANILO; HACHUL, DENISE TESSARIOL; VERONESE, PEDRO; HARDY, CARINA; PISANI, CRISTIANO; et al. Clinical Features, Genetic Findings, and Risk Stratification in Arrhythmogenic Right Ventricular Cardiomyopathy: Data From a Brazilian Cohort. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, v. 16, n. 2, p. 10-pg., 2023-02-01. (16/15223-3)