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Development of customized metallic implants using direct metal laser sintering

Grant number: 16/09350-2
Support type:Research Grants - Visiting Researcher Grant - International
Duration: February 01, 2017 - January 31, 2018
Field of knowledge:Engineering - Materials and Metallurgical Engineering
Principal Investigator:Rubens Maciel Filho
Grantee:Rubens Maciel Filho
Visiting researcher: Miloslav Beres
Visiting researcher institution: Technical University of Kosice (TUKE), Slovakia
Home Institution: Faculdade de Engenharia Química (FEQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil


Additive manufacturing has been incorporated into the medical field since the late 80's and together with CT and MRI techniques allowing to obtain solid biomodels facilitating surgical procedures and reducing risk of failure. Currently, the additive manufacturing allows production of customized implants, tailoring them directly to the patient's needs. Among metallic biomaterials, cobalt-chromium-molybdenum alloys are among the most used materials for craniofacial and orthopedic implants. A surface functionalization is used to incorporate specific antibacterial properties through addition of fluoride ions, favoring osteointegration of an implant and improving its corrosion behavior. The project aims to develop customized implants using metal additive manufacturing. Direct Metal Laser Sintering (DMLS) is a new additive manufacturing technique, producing near net-shape components. A laser beam is used to melt the metal powder in a computer controlled process following a 3D model building up the desired structure layer by layer. The material waste is low, the production preparation time is short and complex structures can be obtained with minimal post-processing and therefore low cost customized implant operations can be produced.Samples will be manufactured from CoCrMo alloys. Besides the microstructural and mechanical characterization, corrosion behavior and wear resistance of these three biomaterials will be evaluated. The alloy produced by the DMLS process will be functionalized through anodizing, for the development of a nanoporous CrO2 biofilm on its surface. In vitro tests will be carried out. In the last stage of the project customized implants made of biomedical alloys CoCrMo alloy using DMLS process will be produced. (AU)

Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
GIRAO, DANIEL DE CASTRO; BERES, MILOSLAV; JARDINI, ANDRE LUIZ; MACIEL FILHO, RUBENS; SILVA, CLEITON CARVALHO; DE SIERVO, ABNER; GOMES DE ABREU, HAMILTON FERREIRA; ARAUJO, WALNEY SILVA. An assessment of biomedical CoCrMo alloy fabricated by direct metal laser sintering technique for implant applications. Materials Science & Engineering C-Materials for Biological Applications, v. 107, FEB 2020. Web of Science Citations: 0.
ANTUNES, L. H. M.; HOYOS, J. J.; FONSECA, E. B.; BERES, M.; DA SILVA FARINA, P. F.; LOPES, E. S. N.; JARDINI, A. L.; MACIEL FILHO, R. Effect of phase transformation on ductility of additively manufactured Co-28Cr-6Mo alloy: An in situ synchrotron X-ray diffraction study during mechanical testing. MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING, v. 764, SEP 9 2019. Web of Science Citations: 1.
BERES, M.; SILVA, C. C.; SARVEZUK, P. W. C.; WU, L.; ANTUNES, L. H. M.; JARDINI, A. L.; FEITOSA, A. L. M.; ZILKOVA, J.; DE ABREU, H. F. G.; FILHO, R. M. Mechanical and phase transformation behaviour of biomedical Co-Cr-Mo alloy fabricated by direct metal laser sintering. MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING, v. 714, p. 36-42, JAN 31 2018. Web of Science Citations: 6.
NOVOTNY, LADISLAV; DE ABREU, HAMILTON FERREIRA GOMES; ZAJAC, JOZEF; BERES, MILOSLAV. Imperfections generation in finite element models of welding. SCIENCE AND TECHNOLOGY OF WELDING AND JOINING, v. 23, n. 2, p. 148-157, 2018. Web of Science Citations: 0.

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