Biocompatibility of the hydrogel used in vitreoretinal surgery

• Grant number: 16/07468-6
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2017
• End date: July 31, 2019
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Octaviano Magalhães Junior
• Grantee: Octaviano Magalhães Junior
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated researchers: Andreia de Araújo Morandim ; Patrícia Alessandra Bersanetti ; Paulo Schor

Abstract

The introduction of vitreoretinal surgery, pars plana vitrectomy, enabled the treatment of major diseases of the retinal diseases such as diabetic retinopathy, macular hole or retinal detachment. Current vitreous substitutes routinely used such as balanced salt solution, air, octalfluoropropane gas or silicone oil have their own advantages and limitations. The use of the hydrogel as vitreous substitute enable a breakthrough in surgical technique and consequent improvement of surgical outcomes. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE OLIVEIRA, RAMON ANTUNES; MURALHA, FELIPE PICANCO; GRUPENMACHER, ALEX TREIGER; MORANDIM-GIANNETTI, ANDREIA DR ARAUJO; BERSANETTI, PATRICIA ALESSANDRA; MAIA, MAURICIO; MAGALHAES JUNIOR, OCTAVIANO. Biocompatibility of polyvinyl alcohol/trisodium trimetaphosphate as vitreous substitute in experimental vitrectomy model in rabbits. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, v. 110, n. 2, JUL 2021. (16/07468-6)