Research Grants 17/15121-9 - Gravidez, Cardiologia - BV FAPESP
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HEMODYNAMIC AND CARDIAC BIOMARKERS IN DORPER SHEEP BREED IN THE PERINATAL PERIOD

Grant number: 17/15121-9
Support Opportunities:Regular Research Grants
Start date: November 01, 2017
End date: October 31, 2019
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal Investigator:Maria Lucia Gomes Lourenço
Grantee:Maria Lucia Gomes Lourenço
Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
Associated researchers:Eunice Oba

Abstract

During pregnancy, the fetus heart suffers numerous changes to form the major blood vessels and thus, become the central organ which pumps blood through rhythmic contractions around the body. The pregnancy diagnosis in sheep incorporates economic value for producers, and, when performed early, in accordance with the ability to quantify the fetuses, it is useful to adapt the nutritional management. Heart rate is an important parameter related to the cardiovascular system of the individual, the presence of diseases and disorders that involve physiological status, and its service monitor to detect changes related to fetal viability and assists in the pregnancy diagnosis. Thus, the objectives of this study will be describe the behavior of electrocardiographic parameters (ECG), echocardiography, normal heart rate (HR), indices of heart rate variability (HRV), blood pressure and its association with biochemical profiles (NT-proBNP) in sheep and neonates. For this study we will use 10 ewes with different ages, the Dorper breed, in all months of gestation (five months) and after childbirth. The sheep and lambs will be evaluated 24 hours, 7 °, 14 °, 21 °, 28 ° and 35 ° day; 2 months, 3 months, 4 months after the birth (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CRUZ-ALEIXO, AMANDA SARITA; LIMA, MAYRA DE CASTRO FERREIRA; ALBUQUERQUE, ANA LUISA HOLANDA DE; TEIXEIRA, RAPHAEL TORTORELLI; DE PAULA, RENATA ALVES; GRANDI, MARINA CECILIA; FERREIRA, DANILO OTAVIO LAURENTI; TSUNEMI, MIRIAM HARUMI; CHIACCHIO, SIMONE BIAGIO; LOURENCO, MARIA LUCIA GOMES. Echocardiographic evaluation in Dorper ovine fetuses: Applications and limitations. VETERINARY MEDICINE AND SCIENCE, v. 7, n. 2, p. 417-423, . (17/15121-9)
CRUZ-ALEIXO, AMANDA SARITA; DE CASTRO FERREIRA LIMA, MAYRA; HOLANDA DE ALBUQUERQUE, ANA LUISA; TORTORELLI TEIXEIRA, RAPHAEL; ALVES DE PAULA, RENATA; GRANDI, MARINA CECILIA; LAURENTI FERREIRA, DANILO OTAVIO; HARUMI TSUNEMI, MIRIAM; BIAGIO CHIACCHIO, SIMONE; GOMES LOURENCO, MARIA LUCIA. Heart rate variability in Dorper sheep in the fetal and neonatal periods until 120 days of age: Use of the technique in the field. JOURNAL OF VETERINARY MEDICAL SCIENCE, v. 83, n. 1, p. 17-27, . (17/15121-9)
CRUZ ALEIXO, AMANDA SARITA; LAURENTI FERREIRA, DANILO OTAVIO; TSUNEMI, MIRIAM HARUMI; CHIACCHIO, SIMONE BIAGIO; GOMES LOURENCO, MARIA LUCIA. Influence of Dorper lamb development from birth to 120 days of age on clinical and echocardiographic parameters. SCIENTIFIC REPORTS, v. 12, n. 1, p. 11-pg., . (17/15121-9)