Correlation between anatomical and psycophisical findings in maculopathies: diabetic macular edema

• Grant number: 07/05533-6
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: March 01, 2008
• End date: February 28, 2010
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Augusto Paranhos Junior
• Grantee: Aline do Lago Coutinho
• Host Institution: Departamento de Oftalmologia. Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil

Abstract

The high resolution of the anatomical findings of the diabetic macular edema (DME) is getting better with the OCT and HRA and it have been used as parameter to evaluate different treatment strategies. On the other side, the functionalevaluation is performed simply with the ETDRS charts of visual acuity most ofthe times. With the advance of the psychophysics tests, there is a chance forbetter functional evaluation on these diseases and in the future would allow usto better characterize the outcome of treatments. Objective: evaluation of the topographic association between anatomicalfindings of DME seen by OCT and HRA and psychophysics tests of magno and coniocell cells subpopulations performed by SAP, SWAP, FDT Matrix and Hyperacuity preferential perimetry. Methodology: prospective, transversal, no controlled study in patients of theRetina section - Federal University of Sao Paulo with the previous diagnosis ofARMD and DME confirmed by OCT and HRA. The patients will be submitted toa psychophysical evaluation with SAP 10-2, SWAP 10-2, FDT Matrix 10-2 andHyperacuity Preferential Perimeter. The anatomic-functional topographicalcorrelation will be performed. (AU)