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Feasibility study of functional Ambulatorial assessment for patients undergoing hematopoietic stem cell transplantation

Grant number: 09/01592-3
Support type:Scholarships in Brazil - Master
Effective date (Start): March 01, 2010
Effective date (End): November 30, 2011
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal researcher:Afonso Celso Vigorito
Grantee:Clarissa Vasconcellos de Souza
Home Institution: Centro de Hematologia e Hemoterapia (HEMOCENTRO). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil


Before, during and after hematopoietic stem cell transplantation (HSCT) procedure patients go throw significant physical, psychological and psychosocial stress and on their return to routine activities they complain about fatigue, worsening of functionality and reduction on their participation in activities that demand physical skills. Aim: This prospective study intends to evaluate the necessities and possibilities of a functional assessment through physioterapeutic exams that can be performed at ambulatorial facilities in a simple and effective way, before and after HSCT. Methods: In the last 5 years, the Hemocentro had a media of 73 patients undergoing HSCT, so we design a possible casuistic of 20 to 25 patients for each type of transplant procedure. The study methods will be: 2 minutes walking test (2MWT), Borg Scale (BS) before and after 2MWT, Grip Strength (GS), Schober Test (ST), and the application of the Human Activity Profile (HAP) questionnaire. Analysis and Results: The analisys will involve physiotherapeutic and clinical data. The relevant results are to characterize the most frequent physical losses in this population, its intensity and moreover guiding preventive measures and better rehabilitation program on post HSCT period. The study intends to include and improve new routine of evaluation and in the follow-up of HSCT patients. (AU)

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