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Features and prognosis of prostate cancer in different age groups: a matched paired analysis.

Grant number: 10/17839-5
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2011
Effective date (End): December 31, 2011
Field of knowledge:Health Sciences - Medicine - Surgery
Principal researcher:Miguel Srougi
Grantee:José Arnaldo Shiomi da Cruz
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Prostate cancer is the most common malignant neoplasm among men worldwide. Several prognostic factors have been accepted in the literature like Gleason score, PSA levels, and percentage of positive fragments at the prostate biopsy. Nevertheless, age has not been formally studied as a prognostic factor in an independently from the already known prognostic factors. The purpose of this study is to compare in different age groups the features and evolution of prostate cancer in patients whose main known prognostic factors are equivalent through a controlled matched-paired analysis in order to analyse the variable age separately from the other prognostic factors already accepted in the literature and determine the real impact of age in the prognosis of prostate cancer.

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