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Elucidation of vitamin B metabolism in the human malaria parasite plasmodium falciparum and their validation as a target for chemotherapy

Grant number: 10/20647-0
Support Opportunities:Scholarships in Brazil - Young Researchers
Start date: December 01, 2010
End date: November 30, 2013
Field of knowledge:Biological Sciences - Biophysics - Cellular Biophysics
Principal Investigator:Carsten Wrenger
Grantee:Carsten Wrenger
Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:09/54325-2 - Elucidation of vitamin B metabolism in the human malaria parasite Plasmodium falciparum and their validation as a target for chemotherapy, AP.JP
News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications (8)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BOSCH, SORAYA S.; KRONENBERGER, THALES; MEISSNER, KAMILA A.; ZIMBRES, FLAVIA M.; STEGEHAKE, DIRK; IZUI, NATALIA M.; SCHETTERT, ISOLMAR; LIEBAU, EVA; WRENGER, CARSTEN. Oxidative Stress Control by Apicomplexan Parasites. BIOMED RESEARCH INTERNATIONAL, . (11/19703-6, 12/12807-3, 11/13706-3, 09/54325-2, 10/20647-0, 13/10288-1, 13/17577-9)
KRONENBERGER, THALES; LINDNER, JASMIN; MEISSNER, KAMILA A.; ZIMBRES, FLAVIA M.; CORONADO, MONIKA A.; SAUER, FRANK M.; SCHETTERT, ISOLMAR; WRENGER, CARSTEN. Vitamin B6-Dependent Enzymes in the Human Malaria Parasite Plasmodium falciparum: A Druggable Target?. BIOMED RESEARCH INTERNATIONAL, . (11/19703-6, 12/12807-3, 11/13706-3, 09/54325-2, 10/20647-0, 13/10288-1, 12/12790-3)
ZIMBRES, FLAVIA M.; TARNOK, ATTILA; ULRICH, HENNING; WRENGER, CARSTEN. Aptamers: Novel Molecules as Diagnostic Markers in Bacterial and Viral Infections?. BIOMED RESEARCH INTERNATIONAL, . (09/54325-2, 12/50393-6, 11/19703-6, 10/20647-0)
ZIMBRES, FLAVIA M.; TARNOK, ATTILA; ULRICH, HENNING; WRENGER, CARSTEN. Aptamers: Novel Molecules as Diagnostic Markers in Bacterial and Viral Infections?. BIOMED RESEARCH INTERNATIONAL, v. 2013, p. 7-pg., . (11/19703-6, 10/20647-0, 12/50393-6, 09/54325-2)
KRONENBERGER, THALES; LINDNER, JASMIN; MEISSNER, KAMILA A.; ZIMBRES, FLAVIA M.; CORONADO, MONIKA A.; SAUER, FRANK M.; SCHETTERT, ISOLMAR; WRENGER, CARSTEN. Vitamin B6-Dependent Enzymes in the Human Malaria Parasite Plasmodium falciparum: A Druggable Target?. BIOMED RESEARCH INTERNATIONAL, v. 2014, p. 11-pg., . (13/10288-1, 10/20647-0, 12/12790-3, 09/54325-2, 11/13706-3, 12/12807-3, 11/19703-6)
PEREIRA, C. A.; SAYE, M.; WRENGER, C.; MIRANDA, M. R.. Metabolite Transporters in Trypanosomatid Parasites: Promising Therapeutic Targets But... How to Deal with Them?. Current Medicinal Chemistry, v. 21, n. 15, p. 1707-1712, . (09/54325-2, 10/20647-0)
BOSCH, SORAYA S.; KRONENBERGER, THALES; MEISSNER, KAMILA A.; ZIMBRES, FLAVIA M.; STEGEHAKE, DIRK; IZUI, NATALIA M.; SCHETTERT, ISOLMAR; LIEBAU, EVA; WRENGER, CARSTEN. Oxidative Stress Control by Apicomplexan Parasites. BIOMED RESEARCH INTERNATIONAL, v. 2015, p. 10-pg., . (13/10288-1, 10/20647-0, 09/54325-2, 11/13706-3, 13/17577-9, 12/12807-3, 11/19703-6)
KRONENBERGER, THALES; SCHETTERT, ISOLMAR; WRENGER, CARSTEN. Targeting the vitamin biosynthesis pathways for the treatment of malaria. Future Medicinal Chemistry, v. 5, n. 7, p. 769-779, . (09/54325-2, 10/20647-0, 11/13706-3)