Effects of exposure to social deprivation stress during adolescence on ethanol self-administration in rats

• Grant number: 11/23558-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2012
• End date: February 28, 2013
• Field of knowledge: Biological Sciences - Pharmacology - Neuropsychopharmacology
• Principal Investigator: Cleopatra da Silva Planeta
• Grantee: Cindy Christine de Freitas Santaguita Nishihara
• Host Institution: Faculdade de Ciências Farmacêuticas (FCFAR). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

The purpose of the present project is to investigate whether the exposure to social deprivation stress during adolescence increases ethanol self-administration in later stages of ontogeny. To this end, adolescent rats will be housed isolated from post-natal day (PND) 28 - 42. After the stress they will be tested for ethanol oral operant self-administration to determine the break point in a progressive ratio schedule and the ethanol intake in a 24-hour binge session. (AU)