Studies of the interaction of semiconductor nanocrystals (Quantum Dots) with organic photosensitizers in the presence of nano-organized structures - models of biological systems

• Grant number: 11/20606-5
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: March 01, 2012
• End date: October 31, 2014
• Field of knowledge: Biological Sciences - Biophysics - Radiology and Photobiology
• Principal Investigator: Iouri Borissevitch
• Grantee: Gustavo Gimenez Parra
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

In this project we intend to study the interaction between water soluble quantum dots (CdSe/ZnS and CdTe) and organic compounds (porphyrins TMPyP and TPPS4 and Cyanic dyes) in the presence of nano-organized models of biological structures. The experimental techniques that we intend to use are the optical absorption and fluorescence spectroscopies, both "steady state" and with high time resolution and an integration system with a time resolved fluorescence and fluorescence lifetime imaging. Micelles formed by ionic surfactants (CTAB and SDS), non-ionic (HPS), copolymer (PLURONIC ® F127) and biopolymers (DNA and proteins) will be used as models of biological structures. The project aim is to clarify the effect of interaction and energy transfer process between quantum dots and other fluorophores applied in diagnostic fluorescence and treatment of diseases by photochemotherapy.

Scientific publications

(5)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BORISSEVITCH, I. E.; PARRA, G. G.; ZAGIDULLIN, V. E.; LUKASHEV, E. P.; KNOX, P. P.; PASCHENKO, V. Z.; RUBIN, A. B.. Cooperative effects in CdSe/ZnS-PEGOH quantum dot luminescence quenching by a water soluble porphyrin. Journal of Luminescence, v. 134, p. 83-87, FEB 2013. (11/20606-5)

PARRA, GUSTAVO G.; PAVANELLI, ANDRE L. S.; FRANCO, LILIAN P.; MAXIMO, LEANDRO N. C.; DA SILVA, ROBERTO S.; BORISSEVITCH, IOURI. Interaction of CdTe-MPA quantum dots with meso-tetra methyl pyridyl porphyrin. Charge transfer complex formation. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, v. 398, JUL 1 2020. (11/20606-5, 16/12707-0)

PARRA, GUSTAVO G.; FERREIRA, LUCIMARA P.; GONCALVES, PABLO J.; SIZOVA, SVETLANA V.; OLEINIKOV, VLADIMIR A.; MOROZOV, VLADIMIR N.; KUZMIN, VLADIMIR A.; BORISSEVITCH, IOURI E.. Stimulation of Cysteine-Coated CdSe/ZnS Quantum Dot Luminescence by meso-Tetrakis (p-sulfonato-phenyl) Porphyrin. NANOSCALE RESEARCH LETTERS, v. 13, FEB 5 2018. (11/20606-5)

PARRA, GUSTAVO G.; BORISSEVITCH, GALINA; BORISSEVITCH, IOURI; RAMOS, ANA P.. Quantum dot effects upon the interaction between porphyrins and phospholipids in cell membrane models. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, v. 45, n. 3, p. 219-227, APR 2016. (12/20946-3, 11/20606-5)

PARRA, GUSTAVO G.; FERREIRA, LUCIMARA P.; GONCALVES, PABLO J.; SIZOVA, SVETLANA V.; OLEINIKOV, VLADIMIR A.; MOROZOV, VLADIMIR N.; KUZMIN, VLADIMIR A.; BORISSEVITCH, IOURI E.. Stimulation of Cysteine-Coated CdSe/ZnS Quantum Dot Luminescence by meso-Tetrakis (p-sulfonato-phenyl) Porphyrin. NANOSCALE RESEARCH LETTERS, v. 13, p. 8-pg., 2018-02-05. (11/20606-5)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

PARRA, Gustavo Gimenez. Interaction of quantum dots with organic photosensitizers in the presence of nano-organized structures. 2015. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (PCARP/BC) Ribeirão Preto.