Kinetic resolution of carbonates derived from Morita-Baylis-Hillman adducts and the use of chiral adducts in the synthesis of 1,8-dihydronaphthryridines and dihydroquinolines

• Grant number: 12/00548-3
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2012
• End date: July 31, 2012
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Fernando Antonio Santos Coelho
• Grantee: Hugo dos Santos
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

This undergraduate research project aims at carrying out kinetic resolution of carbonates derived from Morita-Baylis-Hillman, using an enantioselective allylic hydroxylation. The chiral adducts will be employed as starting material for the synthesis of chiral 1,8-dihydronaphthyridines and dihydroquinolines (AU)