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Development of voltammetric sensors for environmental monitoring of pharmaceutical drugs:oxytetracycline, doxycycline, trimethoprim and sulfamethoxazole

Grant number: 11/10216-5
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): May 01, 2012
Effective date (End): August 31, 2014
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
Principal researcher:Marcelo Firmino de Oliveira
Grantee:Izabel Cristina Eleotério
Home Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

The detection of residues of drugs such as anti-inflammatory drugs, steroid hormones, mainly antidepressants and antibiotics in the environment has concerned researchers since, even when present in concentrations orders of mg to ng L-1. This project will emphasize voltammetric analysis of the antibiotics doxycycline, trimethoprim, oxytetracycline and trimethoprim antibiotics using cyclic voltammetry method to determine their mechanisms electrodic. We will develop voltammetric sensors based on N,N'-ethylenebis(salicylideneaminato)oxovanadium(IV)[VO(Salen)], modified carbon-paste electrode, associated with differential pulse voltammetric methods and square wave for quantitative analysis respective drugs in samples of environmental interest. Will be conducted comparison of results with technique liquid chromatography-mass spectrometry (LC-MS).

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ELEOTERIO, IZABEL C.; BALBINO, MARCO A.; DE ANDRADE, JOSE F.; FERREIRA, BRUNO; SACZK, ADELIR A.; OKUMURA, LEONARDO L.; BATISTA, ANTONIO CARLOS F.; DE OLIVEIRA, MARCELO F.. Analysis of sulfamethoxazole by square wave voltammetry using new carbon paste electrode. JOURNAL OF ELECTROCHEMICAL SCIENCE AND ENGINEERING, v. 8, n. 4, p. 281-289, . (16/23825-3, 11/10216-5)

Please report errors in scientific publications list by writing to: cdi@fapesp.br.