Effect of the sodium trimetaphosphate (TMP) associated to fluoride (F) at concentrations of 100, 250, 500 and 1100 ppm f on the hydroxyapatite (HA): biochemistry and structural analysis

• Grant number: 12/05116-4
• Support Opportunities: Scholarships in Brazil - Master
• Start date: May 01, 2012
• End date: April 30, 2014
• Field of knowledge: Health Sciences - Dentistry - Pediatric Dentistry
• Principal Investigator: Alberto Carlos Botazzo Delbem
• Grantee: José Antonio Santos Souza
• Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil

Abstract

The aim of this study will be to evaluate the effect of different concentrations of sodium trimetaphosphate (TMP) associated with fluoride (F) on hydroxyapatite (HA) solubility, as well as in biochemical and physical properties of HA after a pH-cycle. Synthetic HA powder (1.0 g) will be mixed with solutions of TMP at 0, 0.1, 0.2, 0.4, 0.6, 0.8, 1.0, 2.0, 4.0, 6.0, 8.0 and 10%, associated with fluoride at 0, 100, 250 and 500 ppm F, during 2 min. The precipitates will be filtered, dried for 24 h at 37°C and grinded. After the treatment, HA samples will be submitted to a pH-cycle. Post-cycled HA samples will be analyzed by energy-dispersive X-ray spectroscopy (EDX), infrared spectroscopy transformed Fourier (FTIR) and X-ray diffraction (XRD). Afterwards, the concentration of alkali and acid soluble F, Ca and P will be determined in post-cycled HA, as well as P and F in the supernatant. The data will be tested for normality and homogeneity to choose the statistical analysis more appropriate. (AU)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SOUZA, José Antonio Santos. Efeito do trimetafosfato de sódio e do fluoreto sobre a solubilidade da hidroxiapatita: estudo in vitro. 2014. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Odontologia. Araçatuba Araçatuba.