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Evaluation of the toxic potential of two metallo-insecticides to non-target organisms

Grant number: 12/12019-5
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): October 01, 2012
Effective date (End): July 31, 2016
Field of knowledge:Biological Sciences - Genetics - Mutagenesis
Principal Investigator:Carmem Silvia Fontanetti Christofoletti
Grantee:Raphael Bastão de Souza
Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil


The indiscriminate use of synthetic pesticides has caused concern in the scientific community due to adverse effects in man and in the environment. Aware of this problem, governments of many countries have banned the use of some substances, forcing the development of alternatives with the same efficiency and environmentally safer. Although it has been banned in many countries, the insecticide sulfluramid is still used in Brazil for the control of ants, an agriculture pest. As an effective alternative to the use of sulfluramid, researchers from UNESP and UFSCar developed a Metallo-Insecticide system, whose formula is a natural product complexed with a metal. However, for certification that it is environmentally safe, ecotoxicological tests are necessary. In this sense, this project proposes to examine the toxic potential of this Metallo-insecticide system to non-target organisms through the following tests: reproduction and avoidance test, using the species Folsomia candida (Collembola) and Eisenia andrei (Annelida); mutagenicity, genotoxicity and cytotoxicity tests, using Allium cepa and Tradescantia pallida and a representative of the soil fauna, the millipede Rhinocricus padbergi.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE SOUZA, RAPHAEL BASTAO; DE SOUZA, CLEITON PEREIRA; BUENO, ODAIR CORREA; FONTANETTI, CARMEM SILVIA. Genotoxicity evaluation of two metallic-insecticides using Allium cepa and Tradescantia pallida: A new alternative against leaf-cutting ants. Chemosphere, v. 168, p. 1093-1099, . (12/12019-5)
DE SOUZA, RAPHAEL B.; MOREIRA-DE-SOUSA, CRISTINA; ANSOAR-RODRIGUEZ, YADIRA; MANCINI COELHO, MARIA PAULA; DE SOUZA, CLEITON PEREIRA; BUENO, ODAIR CORREA; FONTANETTI, CARMEM S.. Histopatology and HSP70 analysis of the midgut of Rhinocricus padbergi (Diplopoda) in the evaluation of the toxicity of two new metallic-insecticides. Environmental Science and Pollution Research, v. 27, n. 3, p. 3023-3033, . (12/12019-5)

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