STUDY OF THE DEGRADATION OF ANTIBIOTICS AT TRACE CONCENTRATION BY PHOTO-OXIDATIVE PROCESSES

• Grant number: 12/14889-7
• Support type: Scholarships in Brazil - Post-Doctorate
• Effective date (Start): March 01, 2013
• Effective date (End): August 31, 2016
• Field of knowledge: Engineering - Chemical Engineering - Chemical Process Industries
• Principal Investigator: Antonio Carlos Silva Costa Teixeira
• Grantee: Ana Paula dos Santos Batista
• Home Institution: Escola Politécnica (EP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 13/05041-7 - Photochemical contribution of reactive species on the degradation of organic pollutants using solar simulator and gamma radiation, BE.EP.PD

Abstract

Although antibiotics residues had been found at low concentrations, some studies have reported the promotion of bacterial resistance to pathogens. Therefore, the study of processes that promote degradation of this emerging pollutant degradation is necessary. In this context, this project aims to study the photodegradation of two antibiotics and its residues in aqueous solutions by advanced oxidation process (AOP) (H2O2/UV and photo-Fenton). The measurement of antibiotics concentration and identification of degradation products will be carried out using high performance liquid chromatography coupled to mass spectrometry (LC-MS). The organic matter removal will be followed by Total Organic Carbon (TOC) analysis. Taking into account the degradation process of antibiotics will be carried out in aqueous solution containing the contaminant at different concentration levels, in this work solid phase extraction (SPE) technique will be used. Degradation routes of antibiotics during reaction with hydroxyl radicals will be proposed. It is intended stabilize iron species in the presence of bio-organic surfactants (BOS) during antibiotics photo-oxidation by photo-Fenton process, enabling disposal of this solution without prior pH adjustment. This project also aims to establish scientific research cooperation between the Chemical Systems Engineering Center (CESQ/PQI-EPUSP) and the University of California, as a result of the researcher's training at the foreign institution, also contributing to her international insertion.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BATISTA, ANA PAULA S.; TEIXEIRA, ANTONIO CARLOS S. C.; COOPER, WILLIAM J.; COTTRELL, BARBARA A. Correlating the chemical and spectroscopic characteristics of natural organic matter with the photodegradation of sulfamerazine. WATER RESEARCH, v. 93, p. 20-29, APR 15 2016. Web of Science Citations: 21.

BATISTA, ANA PAULA S.; PIRES, FLAVIO CHIQUETTO C.; TEIXEIRA, ANTONIO CARLOS S. C. The role of reactive oxygen species in sulfamethazine degradation using UV-based technologies and products identification. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, v. 290, p. 77-85, SEP 15 2014. Web of Science Citations: 17.

BATISTA, ANA PAULA S.; PIRES, FLAVIO CHIQUETTO C.; TEIXEIRA, ANTONIO CARLOS S. C. Photochemical degradation of sulfadiazine, sulfamerazine and sulfamethazine: Relevance of concentration and heterocyclic aromatic groups to degradation kinetics. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, v. 286, p. 40-46, JUL 15 2014. Web of Science Citations: 26.