Evaluation ntioxidant, sunscreens, antiglicant and antiacne potential of Sapindus saponaria L and Hancornia speciosa Gomez

• Grant number: 13/10039-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: November 01, 2013
• End date: October 31, 2014
• Field of knowledge: Biological Sciences - Pharmacology - Ethnopharmacology
• Principal Investigator: Regildo Márcio Gonçalves da Silva
• Grantee: Gustavo Rafagnin Martins
• Host Institution: Faculdade de Ciências e Letras (FCL-ASSIS). Universidade Estadual Paulista (UNESP). Campus de Assis. Assis , SP, Brazil

Abstract

The effect caused by oxidative free radicals from the metabolism of O2 occurs naturally in the body. Oxidative stress, increase this condition is correlated to the onset of diseases and can be intensified due to exposure to external factors such as solar radiation, thus causing significant cellular damage, which can lead to accelerated aging of cells. Studies with plant extracts have shown that they contain compounds of pharmacological interest to treat and / or prevent cell damage caused by oxidative stress, which may result in an antioxidant action, sunscreen, anti-acne and antiglicante. Therefore, this project aims to evaluate the potential antioxidant, sunscreen, anti-acne and antiglicante of ethanolic and hydro-alcoholic fruit pericarp of Sapindus soapy and leaves Hancornia speciosa by testing in vitro using spectrophotometric and spectrofluorimetric techniques.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SILVA, REGILDO M. G.; MARTINS, GUSTAVO R.; NUCCI, LAURA M. B.; GRANERO, FILIPE O.; FIGUEIREDO, CELIA C. M.; SANTIAGO, PATRICIA S.; SILVA, LUCIANA P.. Antiglycation, antioxidant, antiacne, and photoprotective activities of crude extracts and triterpene saponin fraction of Sapindus saponaria L. fruits: An in vitro study. ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE, v. 12, n. 9, p. 9-pg., 2022-09-01. (13/10039-1)