|Support type:||Scholarships in Brazil - Master|
|Effective date (Start):||March 01, 2014|
|Effective date (End):||February 28, 2015|
|Field of knowledge:||Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals|
|Principal Investigator:||Roberto Carvalheiro|
|Home Institution:||Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil|
Important changes regarding the cultural and economic characteristics have directed livestock producers to apply modern technologies in order to achieve the genetic progress and increase productivity in animal husbandry. Morphological traits, such as the animal's aplomb, are of great importance the body's sustainment and mobility. Culling process based on defects in the aplombs represents a relevant productive loss. Nowadays, molecular data of livestock species are gaining more attention by the animal breeding programs and producers, because of the implementation of genomic tools. These tools considers the information of a massive number of single nucleotide polymorphism (SNP) present along animal's genome to estimate genomic breeding values with higher accuracy than the traditional phenotype-pedigree evaluation and aid in the selection process (i.e. genomic selection). Another application of this molecular information is to evaluate the existence of significant association of molecular markers (i.e. SNPs) and phenotypes, also known as genome-wide association studies (GWAS). Thus, the objectives of this study are to estimate genetic parameters for aplomb traits in Nellore cattle, as well as conduct GWAS for this trait to identify possible genomic regions that are related to the trait' expression. Phenotypic data from 245 farms will be provided by the PAINT breeding program. The genetic parameters will be estimated using the animal model, by means of a threshold analysis. The GWAS analyses will be conducted by means of the "weighted single step GBLUP" method. The results obtained in this study could provide substantial information for the Nellore breeding program.