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Evaluation of protein Osx and STRO-1 in the Peripheral Ossifying Fibroma

Grant number: 13/14862-4
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date: May 01, 2014
End date: April 30, 2015
Field of knowledge:Health Sciences - Dentistry
Principal Investigator:Estela Kaminagakura Tango
Grantee:Raphaella Silveira Medeiros
Host Institution: Instituto de Ciência e Tecnologia (ICT). Universidade Estadual Paulista (UNESP). Campus de São José dos Campos. São José dos Campos , SP, Brazil

Abstract

This work aims to analyze the microscopic characteristics of the mineralized component of the peripheral ossifying fibroma (POF) and investigate the immunoreactivity of protein osterix (Osx) and STRO-1. Clinicopathological analysis of 30 cases diagnosed as FOP Laboratory of Histopathology will be performed, Department of Biosciences and Oral Diagnosis Institute of Science and Technology / UNESP São José dos Campos, in the period 2000-2010. Data collected will include: age, gender, location and size. The mineralized component of the FOP will be analyzed by conventional light microscopy, the protein expression of Osx and STRO-1 will be investigated by immunohistochemistry. The results will be correlated with the clinicopathological features.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
RIBEIRO EL ACHKAR, VIVIAN NARANA; MEDEIROS, RAPHAELLA DA SILVEIRA; LONGUE, FERNANDA GARGANO; ANBINDER, ANA LIA; KAMINAGAKURA, ESTELA. The role of Osterix protein in the pathogenesis of peripheral ossifying fibroma. Brazilian Oral Research, v. 31, . (13/14862-4)
RIBEIRO EL ACHKAR, VIVIAN NARANA; MEDEIROS, RAPHAELLA DA SILVEIRA; LONGUE, FERNANDA GARGANO; ANBINDER, ANA LIA; KAMINAGAKURA, ESTELA. The role of Osterix protein in the pathogenesis of peripheral ossifying fibroma. BRAZILIAN ORAL RESEARCH, v. 31, p. 7-pg., . (13/14862-4)