Advanced search
Start date
Betweenand

Evaluation of PCL electrospun fibers on the Ti-30Ta alloy surface after TiO2 nanotubes growth

Grant number: 14/14533-3
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): March 01, 2015
Effective date (End): February 28, 2017
Field of knowledge:Engineering - Biomedical Engineering
Cooperation agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
Principal Investigator:Cecilia Amelia de Carvalho Zavaglia
Grantee:Patricia Capellato
Home Institution: Faculdade de Engenharia Mecânica (FEM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Over the last few years, several studies have been carried out in order to develop new materials for biomedical applications. Material surfaces that provide biomimetic morphology, such as nanoscale architectures, have been shown to alter cell/biomaterial interactions. The electrospinning process has been used for producing polymer fibers due in large part to an increased interest in nanoscale properties and technologies. The use of biocompatible polymers for the viability of cell growth is a promising alternative to improve osseointegration. The purpose of this study is the association of the electrospinning process of biocompatible polymer with TiO2 nanotubes on the Ti30Ta alloy surface. Characterization techniques such as SEM - FEG, X-rays, AFM, TGA, DSC and contact angle will be used for samples analyses. Bone marrow stromal cells (BMSCs) will also be used to investigate the short and long-term cellular response of these biomaterials to cellular adhesion, viability, morphology and proliferation. (AU)