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Evaluation of PCL electrospun fibers on the Ti-30Ta alloy surface after TiO2 nanotubes growth

Grant number: 14/14533-3
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): March 01, 2015
Effective date (End): February 28, 2017
Field of knowledge:Engineering - Biomedical Engineering - Medical Engineering
Cooperation agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
Principal researcher:Cecilia Amelia de Carvalho Zavaglia
Grantee:Patricia Capellato
Home Institution: Faculdade de Engenharia Mecânica (FEM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil


Over the last few years, several studies have been carried out in order to develop new materials for biomedical applications. Material surfaces that provide biomimetic morphology, such as nanoscale architectures, have been shown to alter cell/biomaterial interactions. The electrospinning process has been used for producing polymer fibers due in large part to an increased interest in nanoscale properties and technologies. The use of biocompatible polymers for the viability of cell growth is a promising alternative to improve osseointegration. The purpose of this study is the association of the electrospinning process of biocompatible polymer with TiO2 nanotubes on the Ti30Ta alloy surface. Characterization techniques such as SEM - FEG, X-rays, AFM, TGA, DSC and contact angle will be used for samples analyses. Bone marrow stromal cells (BMSCs) will also be used to investigate the short and long-term cellular response of these biomaterials to cellular adhesion, viability, morphology and proliferation. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CAPELLATO, PATRICIA; SACHS, DANIELA; VILELA, FILIPE BUENO; MELO, MIRIAN M.; SILVA, GILBERT; RODRIGUES, GEOVANI; ZAVAGLIA, CECILIA A. DE C.; NAKAZATO, ROBERTO Z.; CLARO, ANA PAULA R. A. Influence of Annealing Temperature on Corrosion Resistance of TiO(2)Nanotubes Grown on Ti-30Ta Alloy. METALS, v. 10, n. 8 AUG 2020. Web of Science Citations: 0.
CAPELLATO, PATRICIA; SACHS, DANIELA; VASCONCELOS, LUCAS V. B.; MELO, MIRIAM M.; SILVA, GILBERT; RANIERI, MARIA G. A.; ZAVAGLIA, CECILIA A. DE C.; NAKAZATO, ROBERTO Z.; ALVES CLARO, ANA P. R. Optimization of Anodization Parameters in Ti-30Ta Alloy. METALS, v. 10, n. 8 AUG 2020. Web of Science Citations: 0.
PATRICIA CAPELLATO; SAMIRA E. A. CAMARGO; GILBERT SILVA; DANIELA SACHS; FILIPE BUENO VILELA; CECILIA A. DE C. ZAVAGLIA; KETUL C. POPAT; ANA P.R. ALVES CLARO. Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 23, n. 6, p. -, 2020. Web of Science Citations: 0.

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