Development and characterization of tough bioactive glass-ceramics

• Grant number: 15/13314-9
• Support type: Scholarships in Brazil - Post-Doctorate
• Effective date (Start): February 01, 2016
• Effective date (End): January 31, 2020
• Field of knowledge: Engineering - Materials and Metallurgical Engineering
• Principal Investigator: Edgar Dutra Zanotto
• Grantee: Maziar Montazerian
• Home Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
• Associated research grant: 13/07793-6 - CEPIV - Center for Teaching, Research and Innovation in Glass, AP.CEPID

Abstract

Field of Research: The present proposal aims to expose the actual interest of the authors on developing a post-doctoral project in the multidisciplinary area of biomaterials, in particular bio-ceramic engineering. Backgrounds: A thorough literature review conducted by the candidate reveals that the fracture toughness of commercial bioactive glass-ceramics (1-2 MPa.m1/2) is still below the desired standards and should be improved to come close to that of human cortical bone (2-12 MPa.m1/2). Additionally, all toughening mechanisms have not been activated in glass-ceramics yet. There are still several toughening routes, such as transformation toughening, bridging, micro cracking and pull out, which can be stimulated by controlled crystallization of different crystals with a variety of morphologies and structures. For instance, chain silicate crystals, such as enstatite, wollastonite, diopside, canasite, etc. have elongated and needle-like morphology that could reinforce glass-ceramics. Furthermore, enstatite undergoes a martensitic transformation from the orthorhombic phase, protoenstatite, to the monoclinic phase, clinoenstatite that develops twinning, which is responsible for unusually high fracture toughness. Glass-ceramics containing such crystals may have higher strength and fracture toughness. General Objective: Therefore, we intend to develop tough bioactive glass-ceramics based on designed microstructures resulting from the internal crystallization of chain-silicate crystals, e.g., enstatite.

Scientific publications

(9)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ZHENG, QIUJU; ZHANG, YANFEI; MONTAZERIAN, MAZIAR; GULBITEN, OZGUR; MAURO, JOHN C.; ZANOTTO, EDGAR D.; YUE, YUANZHENG. Understanding Glass through Differential Scanning Calorimetry. CHEMICAL REVIEWS, v. 119, n. 13, p. 7848-7939, JUL 10 2019. Web of Science Citations: 1.

KARGOZAR, SAEID; MONTAZERIAN, MAZIAR; FIUME, ELISE; BAINO, FRANCESCO. Multiple and Promising Applications of Strontium (Sr)-Containing Bioactive Glasses in Bone Tissue Engineering. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, v. 7, JUL 5 2019. Web of Science Citations: 0.

MONTAZERIAN, MAZIAR; ZANOTTO, EDGAR DUTRA; ECKERT, HELLMUT. A new parameter for (normalized) evaluation of H-index: countries as a case study. SCIENTOMETRICS, v. 118, n. 3, p. 1065-1078, MAR 2019. Web of Science Citations: 0.

KARGOZAR, SAEID; MONTAZERIAN, MAZIAR; HARNZEHLOU, SEPIDEH; KIM, HAE-WON; BAINO, FRANCESCO. Mesoporous bioactive glasses: Promising platforms for antibacterial strategies. Acta Biomaterialia, v. 81, p. 1-19, NOV 2018. Web of Science Citations: 11.

DEUBENER, J.; MONTAZERIAN, M.; KRUEGER, S.; PEITL, O.; ZANOTTO, E. D. Heating rate effects in time-dependent homogeneous nucleation in glasses. Journal of Non-Crystalline Solids, v. 474, p. 1-8, OCT 15 2017. Web of Science Citations: 6.

MONTAZERIAN, MAZIAR; ZANOTTO, EDGAR DUTRA; ECKERT, HELLMUT. Bibliometrics in glass and other sciences: A Plea for reason. INTERNATIONAL JOURNAL OF APPLIED GLASS SCIENCE, v. 8, n. 3, SI, p. 352-359, SEP 2017. Web of Science Citations: 1.

MONTAZERIAN, MAZIAR; ZANOTTO, EDGAR D. A guided walk through Larry Hench's monumental discoveries. Journal of Materials Science, v. 52, n. 15, SI, p. 8695-8732, AUG 2017. Web of Science Citations: 6.

MONTAZERIAN, MAZIAR; ZANOTTO, EDGAR DUTRA. Bioactive and inert dental glass-ceramics. Journal of Biomedical Materials Research Part A, v. 105, n. 2, p. 619-639, FEB 2017. Web of Science Citations: 23.

MONTAZERIAN, MAZIAR; ZANOTTO, EDGAR DUTRA. History and trends of bioactive glass-ceramics. Journal of Biomedical Materials Research Part A, v. 104, n. 5, p. 1231-1249, MAY 2016. Web of Science Citations: 30.