Influence of air pollution in patients with multiple sclerosis

• Grant number: 15/18613-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: January 01, 2016
• End date: December 31, 2017
• Field of knowledge: Physical Sciences and Mathematics - Geosciences - Meteorology
• Principal Investigator: Marina Piacenti da Silva
• Grantee: Fernanda Rodrigues Diniz
• Host Institution: Faculdade de Ciências (FC). Universidade Estadual Paulista (UNESP). Campus de Bauru. Bauru , SP, Brazil

Abstract

The study of particulate material in air pollution has been a major issue in air quality research, once these components can cause serious problems to the environment and humans. Among the numerous diseases that may be associated with pollution and climate conditions, it is Multiple Sclerosis (MS), consisting of an autoimmune disease that affects the central nervous system causing demyelination in neuronal cells. In this work, will be evaluate the correlation between meteorological variables, particulate matter concentrations in the air of the city of São Paulo and the clinical condition of patients suffering with MS between 2000 and 2014. With the support of the Multiple Sclerosis Brazilian Association (ABEM) , questionnaires will be applied in patients with MS to obtain prognostic and clinical data. In addition, air quality data and particulate matter concentration will be obtained from reports of air quality Environmental Company of the State of São Paulo (CETESB). Expected results of this study are the understanding of which particulate material specifically affects patients with autoimmune diseases such as multiple sclerosis. In addition, the results of this work can help to correlate chronic exposure to pollution with the clinical aspects of MS patients. Once correlations are established between clinical features of patients with the meteorological variables and levels of MP, containment policies and management of pollution can benefit and improve the quality of life of patients suffering with pollution.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DINIZ, FERNANDA RODRIGUES; NARUKAWA IWABE, CLARA MIHO; PIACENTI-SILVA, MARINA. Valuation of the human thermal discomfort index for the five Brazilian regions in the period of El Nino-Southern Oscillation (ENSO). INTERNATIONAL JOURNAL OF BIOMETEOROLOGY, v. 63, n. 11, SI, p. 1507-1516, NOV 2019. (15/18613-4, 15/22864-2)