Effects of antifouling booster biocides irgarol and diuron on endocrine system of soft-bottom flatfish Pleuronichthys verticalis (Jordan & Gilbert, 1880)

• Grant number: 16/01091-8
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• Start date: May 19, 2016
• End date: May 18, 2017
• Field of knowledge: Physical Sciences and Mathematics - Oceanography - Biological Oceanography
• Principal Investigator: Denis Moledo de Souza Abessa
• Grantee: Lucas Buruaem Moreira
• Supervisor: Daniel Schlenk
• Host Institution: Instituto de Biociências (IB-CLP). Universidade Estadual Paulista (UNESP). Campus Experimental do Litoral Paulista. São Vicente , SP, Brazil
• Institution abroad: University of California, Riverside (UCR), United States
• Associated to the scholarship: 13/15482-0 - Establishment of site-specific sediment quality guidelines for the Coast of São Paulo state: scientific basis for the creation of a national legislation, BP.PD

Abstract

Recently, irgarol and diuron have been the most commonly used biocides in antifouling paints and their main impact is related to its presence in the aquatic environment and ecological risks of adverse biological effects on non-target species. Data on the toxicity of these compounds are known but studies evaluating specific responses such as endocrine activity are limited. The main goal of this research project is to assess potential effects of the antifouling biocides irgarol and diuron on endocrine responses of the marine hornyhead turbot Pleuronichthys verticalis exposed to environmental concentrations of both compounds. In vitro bioassays will be applied to screen endocrine activity of the biocides and then, changes in expression of genes involved in the endocrine pathways will be investigated. The results of this research will be important to understand disturbances endocrine system of fish related to exposure of environmental concentration of antifouling biocides. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MOREIRA, LUCAS BURUAEM; DIAMANTE, GRACIEL; GIROUX, MARISSA; XU, ELVIS GENBO; DE SOUZA ABESSA, DENIS MOLEDO; SCHLENK, DANIEL. Changes in thyroid status of Menidia beryllina exposed to the antifouling booster irgarol: Impacts of temperature and salinity. Chemosphere, v. 209, p. 857-865, OCT 2018. (16/01091-8)

MOREIRA, LUCAS BURUAEM; DIAMANTE, GRACIEL; GIROUX, MARISSA; COFFIN, SCOTT; XU, ELVIS GENBO; ABESSA, DENIS MOLEDO DE SOUZA; SCHLENK, DANIEL. Impacts of Salinity and Temperature on the Thyroidogenic Effects of the Biocide Diuron in Menidia beryllina. Environmental Science & Technology, v. 52, n. 5, p. 3146-3155, MAR 6 2018. (16/01091-8)