Correlation between intra-abdominal and intrabladder pressure of horses in supine position or lateral recumbency

• Grant number: 16/00496-4
• Support Opportunities: Scholarships in Brazil - Master
• Start date: July 01, 2016
• End date: December 31, 2017
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Paulo Aléscio Canola
• Grantee: Vanessa Barroco de Paula
• Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil

Abstract

The importance of intra-abdominal pressure and the repercussions of its variations over equine morbidity and mortality only were brought to attention a bit more than a decade ago. However, the results so far have not been encouraging and the repercussions of intra-abdominal hypertension and abdominal compartmental syndrome in this species are still mere speculations. This is mainly due to the impossibility of estimating intra-abdominal pressure (IAP) in this species through indirect methods, in similarity to what is routinely performed in human medicine. With this in mind, we seek to correlate intra-abdominal pressure directly (invasively)-obtained with intrabladder pressure of horses. For that purpose, at least 10 adult horses, male (either stallion or gelding) and female, weighting between 350 and 500kg and with 3.5 to 12 years, absent from any disease of the gastrointestinal or urinary tract will be used as subjects in our study. Clinical examination and complete blood count will precede inclusion on the study, and elective surgeries not related to the gastrointestinal or urinary tract will be criteria for inclusion, with owner consent. Intra-abdominal pressure will be recorded through midline insertion of a teat cannula connected to a fluid-filled system used for monitoring central venous pressure (CVP). Intrabladder pressure will be recorded by using a methodology described and validated for this purpose in humans. The subjects will be kept in supine position or lateral recumbency under general anesthesia. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE PAULA, VANESSA B.; CANOLA, PAULO A.; RIVERA, GABRIELA G.; FILHO, DARCIO Z.; AMARAL, GABRIEL P. D.; FERRAZ, GUILHERME C.; FERRAUDO, ANTONIO S.; CANOLA, JULIO C.. Intrabladder pressure as predictor of intraabdominal pressure in horses. PLoS One, v. 14, n. 10, OCT 10 2019. (16/00496-4)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

PAULA, Vanessa Barroco de. Intrabladder pressure as a predictor of intra-abdominal pressure of horses in supine position or lateral recumbency. 2018. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal Jaboticabal.