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Study of PBAT mulch films: photodegradation, biodegradation and its cytotoxic, genotoxic and mutagenic effects in Allium cepa and human hepatoma HepG2 cells

Grant number: 16/10777-0
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): August 01, 2016
Effective date (End): July 31, 2019
Field of knowledge:Interdisciplinary Subjects
Principal researcher:Ana Rita Morales
Grantee:Patrícia Moraes Sinohara Souza
Home Institution: Faculdade de Engenharia Química (FEQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

The use of plastic films for soil covering (mulching) is widely disseminated in agriculture. However, the use of these films is associated with the negative environmental impact of waste generation, demanding costs for its destination. During its application on the field, these materials are exposed to solar radiation and the process of photodegradation may occur, compromising important properties as tensile strength and block light transmission. In addition, photodegradation can lead to crosslinking of the polymer chains, which may have a negative influence on the biodegradation process. In this context this research project proposes to evaluate additives carbon black and light stabilizers (Tinuvin 783 and Vitamin E) on photodegradation process of the biodegradable polymer poly (adipate-co-butylene terephthalate) -PBAT. The optimized formulations obtained by experimental design will be characterized by biodegradation, citotoxicity, genotoxicity and mutagenicity analysis. Taking into account the eventual exposition of vetetable organisms and humans to mulch degradation products, the toxic effects will be analysed in Allium cepa and human hepatoma HepG2 cells.

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SINOHARA SOUZA, PATRICIA MORAES; DEROLDO SOMMAGGIO, LAIS ROBERTA; MARIN-MORALES, MARIA APARECIDA; MORALES, ANA RITA. PBAT biodegradable mulch films: Study of ecotoxicological impacts using Allium cepa, Lactuca sativa and HepG2/C3A cell culture. Chemosphere, v. 256, OCT 2020. Web of Science Citations: 0.
SINOHARA SOUZA, PATRICIA MORAES; COELHO, FELIPE MOURAO; DEROLDO SOMMAGGIO, LAIS ROBERTA; MARIN-MORALES, MARIA APARECIDA; MORALES, ANA RITA. Disintegration and Biodegradation in Soil of PBAT Mulch Films: Influence of the Stabilization Systems Based on Carbon Black/Hindered Amine Light Stabilizer and Carbon Black/Vitamin E. JOURNAL OF POLYMERS AND THE ENVIRONMENT, v. 27, n. 7, p. 1584-1594, JUL 2019. Web of Science Citations: 0.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.