A study on the stability and the decomposition processes of bambus6uril

• Grant number: 16/18523-8
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: October 01, 2016
• End date: September 30, 2017
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
• Principal Investigator: Grégoire Jean-François Demets
• Grantee: Letícia Testa
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Inspired in the organic macrocycles cucurbituril and hem-cucurbituril, bamabusuril (BU6) was synthesized in 2010 from the condensation of 2,4-dimethylglycoluril and formaldehyde in HCl, where Cl- anions act as cyclization templates. Its structure reminds cucurbituril, which is also formed by 6 units glycolurilic monomers, but it is less rigid and displays a huge affinity for anions, just like semi-cucurbituril. Its solubility is also different, especially when it is complexed with Cl- anions, who enhance their solubility in different solvents. However, bambusuril is not as stable in concentrate HCl as its homologues. The aim of this project is to provoke and control the decomposition of BU6, to understand its mechanism and to discover what are its limits. These answers will help solving synthesis problems, and develop new synthetic routes, with high yields. It will help us to understand the chemistry of the whole urilic macrocycles family.