Assessment of the impact of eosinophilic myocarditis in patients on the waiting list for heart transplantation in inotropic drugs

• Grant number: 16/23770-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: June 01, 2017
• End date: May 31, 2018
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Fernando Bacal
• Grantee: Vinícius Vitor de Oliveira
• Host Institution: Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil

Abstract

Eosinophilic myocarditis (EM) is a rare myocardial disorder in autopsy studies, however with a high incidence among patients in the waiting list for a heart transplant, probably due to the prolonged use of dobutamine. EM can worsen the state of the patient with CHF, because they have already low cardiac reserve. Furthermore, its variable clinical manifestation and non-specific heart signs make the antemortem diagnosis difficult. In this study, we present an evaluation of the impact of eosinophilic myocarditis on patients in the waiting list for a heart transplant taking inotropic drugs such as dobutamine. (AU)