Acute effect of automatic mechanical peripheral stimulation on the standard of activation of ankle muscles during the march in individuals with Parkinson Disease

• Grant number: 17/07434-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2017
• End date: December 31, 2018
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Nise Ribeiro Marques
• Grantee: Vinicius Christianini Moreno
• Host Institution: Centro de Ciências da Saúde. Universidade do Sagrado Coração (USC). Bauru , SP, Brazil

Abstract

Parkinson's disease is a disease that mainly affects the elderly population and is characterized by the symptoms of akinesia, tremor, muscle stiffness and bradykinesia. With the progression of the disease, a disturbance in gait, known as freezing, manifests itself in patients, increasing the incidence of falls and reducing the quality of life. Automatic mechanical peripheral pacing (AMP) is applied by means of a therapeutic device that is adjusted to the patient's feet to provide pressure at two points in the plantar region to generate a painful stimulus. Objective: To analyze the effect of an AMP session on the recruitment pattern (activation, co-contraction and onset) of the ankle stabilizer muscles during gait in individuals with Parkinson's disease. Methods: Individuals diagnosed with Parkinson's disease, recruited from a specific physical activity group, will be evaluated. Patients will be assessed by the Hoehn and Yahr disability scale and the unified Parkinson's Disease Assessment Scale (UPDRS). The electromyographic (EMG) signals of the medial and lateral gastrocnemius and soleus muscles will be collected during maximal voluntary isometric contractions (MVIC) and during gait. Footswitches will also be placed in the calcaneus and at the base of the hallux to determine the gait phases. Two interventions will be performed: the AMP protocol and the placebo in the same anatomical points of AMP. The order of conditions will be set at random. The gait evaluation will be carried out on a footbridge of 20 meters in length, in which will be discarded the passes made in the initial and final five meters for data analysis. Participants will be advised to walk at preferred speed and will be considered for the past 10 analysis. A minimum period of 72 hours will be given of interval between each collection. The pattern of muscular activation will be analyzed by means of muscle activation, calculated by the normalized linear envelope; By muscular co-contraction between medial gastrocnemius / soleus and lateral gastrocnemius / soleus; And by the onset of these muscles. Data will be compared using appropriate statistical tests and the level of significance will be adjusted at p <0.05. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MARQUES, NISE RIBEIRO; KURODA, MARINA HIROMI; MORENO, VINICIUS CHRISTIANINI; ROBERTO ZAMUNER, ANTONIO; BARBIERI, FABIO AUGUSTO. Effects of automatic mechanical peripheral stimulation on gait biomechanics in older adults with Parkinson's disease: a randomized crossover clinical trial. AGING CLINICAL AND EXPERIMENTAL RESEARCH, v. 34, n. 6, p. 9-pg., 2022-04-06. (17/07434-7, 17/08232-9)