Evaluation of peroxide presence in saliva in at-home bleaching: randomized clinical trial

• Grant number: 16/25644-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: October 01, 2017
• End date: September 30, 2018
• Field of knowledge: Health Sciences - Dentistry
• Principal Investigator: Alessandra Buhler Borges
• Grantee: Paula Ayumi Sakassegawa
• Host Institution: Instituto de Ciência e Tecnologia (ICT). Universidade Estadual Paulista (UNESP). Campus de São José dos Campos. São José dos Campos , SP, Brazil

Abstract

The aim of this study is to evaluate the presence of peroxide in saliva in the at-home bleaching systems with prefilled whitening trays and conventional fabricated trays in a randomized clinical trial. Sixteen volunteers will participate in the study after signing a free and informed consent form. The volunteers will be randomly divided in two groups: conventional fabricated trays filled with 10% hydrogen peroxide (HP) and prefilled whitening trays with 10% hydrogen peroxide. The whitening treatment will be accomplished 1x/day, during 30 min for HP. During the treatment, saliva samples will be collected in seven times (0, 1 min; 5 min; 15 min; 31 min; 35 min; and 45 min). The saliva samples will be submitted to photometric analysis based on aminoantiprin reaction for peroxidase activity measurement using a spectrophotometer. Data will be collected for each volunteer at each stage and means will be submitted to appropriate statistical analysis, considering the significance level of 5%. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MAILART, M. C.; SAKASSEGAWA, P. A.; TORRES, C. R. G.; PALO, R. M.; BORGES, A. B.. Assessment of Peroxide in Saliva During and After At-home Bleaching With 10% Carbamide and Hydrogen Peroxide Gels: A Clinical Crossover Trial. Operative Dentistry, v. 45, n. 4, p. 368-376, JUL-AUG 2020. (16/13044-4, 16/25644-6)

MAILART, MARIANE C.; SAKASSEGAWA, PAULA A.; SANTOS, KARINE C.; TORRES, CARLOS R. G.; PALO, RENATO M.; BORGES, ALESSANDRA B.. One-year follow-up comparing at-home bleaching systems outcomes and the impact on patient's satisfaction: Randomized clinical trial. Journal of Esthetic and Restorative Dentistry, v. 33, n. 8, AUG 2021. (16/13044-4, 16/25644-6)