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Effect of gel renewal during in-office dental bleaching using violet led light as photo-accelerator. a randomized blind clinical trial

Grant number: 18/16555-5
Support Opportunities:Regular Research Grants
Duration: November 01, 2018 - May 31, 2020
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal Investigator:Karen Muller Ramalho
Grantee:Karen Muller Ramalho
Host Institution: Universidade Ibirapuera (UNIB). Campus Chácara Flora. São Paulo , SP, Brazil
Associated researchers:Patricia Moreira de Freitas Costa e Silva ; Shady Abdul Amir Youssef


Dental whitening is a very frequent requirement for patients in a dental office as it is an effective and conservative way to improve the appearance of a smile in comparison to invasive restorative techniques. New equipment and products are frequently launched in the dental market for the optimization of tooth whitening. Considering the lack of studies related to the violet LED light (405-410nm), recently launched in the Brazilian market, applied to tooth whitening, as well as the lack of protocols for its use, this study aims to evaluate if bleaching gel renewal during dental office whitening associated with Violet LED light interferes with final color result and postoperative sensitivity in a randomized, blinded, split-mouth study. Thirty-three volunteers will be selected to participate in the study (n = 33), and the study groups will be: G1 (Permanence of the Whitening Gel on the tooth enamel for 15 minutes) and G2 (3 Whitening Gel exchanges every 5 minutes - Totalizing 15 minutes). In both G1 and G2, the arcades will be illuminated with the Violet LED (405-410nm). In the same patient the two treatments (G1 and G2) will be performed, with a split-mouth protocol. The primary outcome will be immediate and mediated color change, quantitatively assessed by colorimetric (color scale) and spectrophotometry tests. Dental sensitivity will also be evaluated during and after tooth whitening using the VAS pain scale. There will be 2 whitening sessions with a 7-day interval between them. The alteration of color and presence of sensitivity will also be evaluated at the times of 14 days and 2 months after the whitening ends. A gel containing 35% hydrogen peroxide will be used. The final color evaluator and responsible for interviewing the patient about the sensitivity will be blind as to which treatment was applied on each side of the patient's arcade. The statistical test will be applied according to the normality of the data. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE SOUZA, BIANCA ROSSI; NEVES LAGO, ANDREA DIAS; FERREIRA, LEILA SOARES; MAYER-SANTOS, ERIC; DE FREITAS, PATRICIA MOREIRA; MORIMOTO, SUSANA; RAMALHO, KAREN MULLER. In-office bleaching protocols using violet LED: A split mouth case report. Photodiagnosis and Photodynamic Therapy, v. 36, . (18/16555-5)

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