Comparison of tissue healing after incisions with diode laser, electrocautery and conventional scalpel: histomorphometric analysis in rats

• Grant number: 17/19363-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2018
• End date: February 28, 2019
• Field of knowledge: Health Sciences - Dentistry - Oral and Maxillofacial Surgery
• Principal Investigator: Valfrido Antonio Pereira Filho
• Grantee: Cássio Amaro Comachio
• Host Institution: Faculdade de Odontologia (FOAr). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

The aim of this study is to compare through histomorphometric analysis the tissue repair of wounds in the back of rats created by incisions performed with three different types of instruments (diode laser, electrocautery, and conventional scalpel) in different periods of the healing process. Therefore, 30 male rats (Rattus novergicus albinus, Holtzman variety) with a body weight of 350g and age varying between 3 to 4 months will be selected. All animals will receive the incisions by the three methods (diode laser, electrocautery, and conventional scalpel) and will be randomly divided into 5 groups with 6 animals each group according to the experimental period (G1: 24 hours after the surgery; G2: 48 hours after the surgery; G3: 72 hours after the surgery; G4: 7 days after the surgery; G5: 14 days after the surgery). After samples histological processing and histomorphometric analysis, the data will be collected and submitted to statistical analysis. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

TORRES-AUGUSTO NETO, RENATO; COMACHIO, CASSIO AMARO; DE ALMEIDA, LILIAN CALDAS QUIRINO; DE AZAMBUJA CARVALHO, PEDRO HENRIQUE; DOS SANTOS TRENTO, GUILHERME; PEREIRA-FILHO, VALFRIDO ANTONIO. Tissue response to different incision tools in animal model. ORAL AND MAXILLOFACIAL SURGERY-HEIDELBERG, v. N/A, p. 8-pg., 2022-08-02. (17/19363-7)